VP2抗体

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     Anti-TDO2 Antibody (N-term) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG,  (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.    

  
  

**Background of VP2 Antibodies**

VP2 (Viral Protein 2) is a structural protein critical to the assembly and infectivity of several viruses, most notably in the *Parvoviridae* family (e.g., canine parvovirus, feline panleukopenia virus) and *Reoviridae* (e.g., rotavirus). In parvoviruses, VP2 forms the primary capsid, mediating host cell receptor binding, viral entry, and antigenic presentation. Antibodies targeting VP2 are central to immune responses, as they neutralize viral infectivity by blocking receptor interactions or destabilizing capsid integrity.

VP2 antibodies are widely used in diagnostics (e.g., ELISA, immunofluorescence) and research to detect viral infections or study capsid dynamics. In vaccine development, recombinant VP2 self-assembles into virus-like particles (VLPs), which elicit potent neutralizing antibodies without infectious material. For example, VP2-based vaccines are effective against canine parvovirus and poultry pathogens like infectious bursal disease virus (IBDV).

In rotaviruses, VP2 is an inner capsid protein involved in RNA replication and packaging. Antibodies against rotavirus VP2 are less common in diagnostics but aid in understanding replication mechanisms. Cross-reactivity studies of VP2 antibodies also shed light on evolutionary relationships among viral strains.

Overall, VP2 antibodies serve as vital tools for virology research, therapeutic development, and understanding host-pathogen interactions across diverse viral families.