KLF2抗体

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     Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)    

  
  

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     Western blot analysis using KLF2 mouse mAb against A431 (1), U937 (2), NIH/3T3 (3), Raw264.7 (4), SPC-A-1 (5), SK-MES-1 (6), and MOLT4 (7) cell lysate.    

  
  

**Background of KLF2 Antibody**

The KLF2 (Krüppel-like factor 2) antibody is a crucial tool for studying the expression and function of KLF2. a transcription factor belonging to the Krüppel-like factor (KLF) family. KLF2 regulates diverse biological processes, including immune regulation, vascular endothelial cell homeostasis, glucose metabolism, and adipogenesis. It is notably involved in T-cell survival, differentiation, and suppression of pro-inflammatory responses, making it a key player in immune tolerance and cardiovascular health.

KLF2 antibodies are widely used in research to detect KLF2 protein levels via techniques like Western blotting, immunohistochemistry, and flow cytometry. These antibodies aid in exploring KLF2's role in diseases such as atherosclerosis, cancer, and autoimmune disorders. For instance, reduced KLF2 expression is linked to endothelial dysfunction in cardiovascular diseases, while its upregulation in certain cancers may influence tumor progression.

Developed in various host species (e.g., rabbit, mouse), KLF2 antibodies are validated for specificity and sensitivity, often through knockout (KO) controls or siRNA knockdown experiments. Their applications extend to preclinical studies, helping to elucidate KLF2's interactions with signaling pathways like NF-κB and MAPK. As KLF2 gains attention as a therapeutic target, its antibody remains indispensable for mechanistic and translational research in immunology, oncology, and vascular biology.