LGALS1抗体

+ +

•  

   

     Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)    

  
  

•  

   

     Flow cytometric analysis of Hela cells using LGALS1 mouse mAb (green) and negative control (red).    

  
  

•  

   

     Immunohistochemical analysis of paraffin-embedded human lung cancer tissues using LGALS1 mouse mAb with DAB staining.    

  
  

•  

   

     Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using LGALS1 mouse mAb with DAB staining.    

  
  

**Background of LGALS1 Antibody**

LGALS1 (Galectin-1) is a protein encoded by the *LGALS1* gene, belonging to the galectin family of β-galactoside-binding lectins. It plays a multifaceted role in cellular processes, including cell adhesion, proliferation, apoptosis, and immune regulation. Galectin-1 is expressed in various tissues and cell types, such as immune cells, endothelial cells, and neurons, and is involved in modulating inflammatory responses, angiogenesis, and tumor progression. Its dual role in cancer—acting as both a tumor suppressor and promoter—depends on context-specific factors like microenvironmental cues and post-translational modifications.

LGALS1 antibodies are valuable tools for studying galectin-1's expression patterns, localization, and functional roles in physiological and pathological states. They are widely used in techniques like Western blotting, immunohistochemistry (IHC), and flow cytometry to detect galectin-1 in research areas spanning oncology, immunology, and neurobiology. For instance, LGALS1 antibodies help elucidate its immunosuppressive effects in tumor microenvironments or its neuroprotective roles in neurodegenerative diseases. Dysregulation of galectin-1 is linked to cancers, chronic inflammation, and autoimmune disorders, making it a potential therapeutic target. Antibodies against LGALS1 also serve as investigative probes for developing galectin-1-targeted therapies, including inhibitors to block its immunosuppressive or pro-angiogenic activities.