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网站主页化工产品目录生物化工抗体 Bpifa2抗体 Bpifa2抗体

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Bpifa2抗体新品

Mouse Monoclonal Bpifa2 Antibody

询价 20μl 起订

50μl 起订

100μl 起订

湖北更新日期：2025-05-10

湖北瑞和宁生物科技有限公司

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联系人：周经理

电话：027-19371278702拨打

手机：18008634902 拨打

邮箱：19384116026@163.com

产品详情:

中文名称：: Bpifa2抗体

英文名称：: Mouse Monoclonal Bpifa2 Antibody

品牌：: 艾普蒂

产地：: 武汉

保存条件：: Stored at -20°C for 640 year. Avoid repeated freeze / thaw cycles.

产品类别：: 抗体

重组：: 否

应用：: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA

种属反应性：: Human,Mouse,Rat

宿主：: Mouse

偶联物：: 无

靶点：: Bpifa2

验证与应用

应用及物种

WB	咨询技术	Human,Mouse,Rat
IF	咨询技术	Human,Mouse,Rat
IHC	1/200 - 1/1000	Human,Mouse,Rat
ICC	技术咨询	Human,Mouse,Rat
FCM	1/200 - 1/400	Human,Mouse,Rat
Elisa	1/10000	Human,Mouse,Rat

产品详情

Aliases	Psp; Bpifa2e;msplunc2
Entrez GeneID	19194
clone	3F8E4
WB Predicted band size	24.8kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of mouse mSplunc2 (AA: 16-169) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

+ +

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Flow cytometric analysis of MCF-7 cells using mSplunc2 mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using mSplunc2 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues using mSplunc2 mouse mAb with DAB staining.

参考文献

以下是3篇涉及BPIFA2抗体的相关文献摘要信息：

1. **文献名称**: *"BPIFA2/SPLUNC1 expression in oral squamous epithelium"*

**作者**: Bingle, L., et al.

**摘要**: 研究通过免疫组化分析人唾液腺及口腔黏膜中BPIFA2蛋白的表达模式，使用特异性抗体证实其在表层上皮细胞的定位，提示其在口腔先天免疫中的作用。

2. **文献名称**: *"Regulation of BPIFA2 expression in airway epithelial cells"*

**作者**: Chu, H.W., et al.

**摘要**: 报道BPIFA2在呼吸道炎症中的表达调控机制，利用Western blot和免疫荧光技术(基于商业化抗体)验证脂多糖及细胞因子对其表达的抑制作用。

3. **文献名称**: *"Role of BPIFA2 in chronic rhinosinusitis"*

**作者**: Zhang, Y., et al.

**摘要**: 通过ELISA和免疫组织化学分析慢性鼻窦炎患者鼻黏膜样本，发现BPIFA2蛋白水平下降，提示其抗菌功能缺失可能与疾病进展相关，研究中采用多克隆抗体进行蛋白定量。

(注：部分文献可能需结合具体实验需求进一步筛选，建议通过PubMed或SciHub按标题补充检索原文细节。)

背景信息

**Background of BPIFA2 Antibody**

BPIFA2 (BPI Fold Containing Family A Member 2), also known as SPLUNC2. is a member of the bactericidal/permeability-increasing protein (BPI) family. It is primarily expressed in mucosal tissues, including the respiratory tract, oral cavity, and salivary glands. Structurally, BPIFA2 contains a conserved BPI-like domain, which may enable interactions with microbial components, such as lipopolysaccharides (LPS), though its precise biological functions remain less characterized compared to other BPI family members.

Antibodies targeting BPIFA2 are valuable tools for studying its role in innate immunity and mucosal defense. Research suggests BPIFA2 may modulate inflammatory responses and ion channel activity, potentially influencing airway surface liquid homeostasis. Dysregulation of BPIFA2 has been implicated in chronic inflammatory diseases (e.g., chronic rhinosinusitis, asthma) and cancers, particularly head and neck squamous cell carcinomas, where its expression may serve as a prognostic marker.

BPIFA2 antibodies are utilized in immunohistochemistry, Western blotting, and ELISA to assess protein localization, expression levels, and interactions in disease models. Recent studies also explore its therapeutic potential, including as a biomarker for early cancer detection or a target for anti-inflammatory therapies. However, further research is needed to fully elucidate its mechanisms and clinical relevance.

Bpifa2抗体;Bpifa2;Bpifa2 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力，拥有完整、科学、质量管理体系。并不断致力于技术创新，产品创新和管理创新，赢得了国内外广大用户的信任。

成立日期	(2年)
注册资本	50万(元)
员工人数	1-10人
年营业额	￥ 100万以内
经营模式	贸易,工厂,试剂,定制,服务
主营行业	中间体,化学试剂