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SSTR5抗体

Rabbit Polyclonal SSTR5 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
湖北 更新日期:2025-05-09

湖北瑞和宁生物科技有限公司

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产品详情:

中文名称:
SSTR5抗体
英文名称:
Rabbit Polyclonal SSTR5 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 225 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
SSTR5

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesSS-5-R
WB Predicted band size39 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human SSTR5
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human heart tissue lysate, Primary antibody: P04474(SSTR5 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P04474(SSTR5 Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P04474(SSTR5 Antibody) at dilution 1/40. (Original magnification: ×200)    


           

参考文献

目前我无法直接访问实时数据库或具体文献内容,以下为示例格式的模拟参考文献(非真实文献)。建议通过PubMed、Google Scholar等平台检索实际文献:

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**示例1**

**文献名称**: "SSTR5 Antibody Development for Neuroendocrine Tumor Targeting"

**作者**: Smith A, et al.

**摘要**: 研究开发了一种高特异性SSTR5单克隆抗体,通过免疫组化验证其在胃肠胰神经内分泌肿瘤中的高表达,提示其作为靶向治疗载体的潜力。

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**示例2**

**文献名称**: "Comparative Analysis of SSTR5 Antibody Specificity in Pituitary Adenomas"

**作者**: Zhang L, et al.

**摘要**: 对比了多种市售SSTR5抗体在垂体腺瘤组织中的染色特异性,发现克隆号XX的抗体灵敏度最高,为临床诊断提供参考标准。

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**示例3**

**文献名称**: "SSTR5 Antibody-Conjugated Nanoparticles for Targeted Drug Delivery"

**作者**: Patel R, et al.

**摘要**: 构建了SSTR5抗体偶联的纳米颗粒,体外实验显示其可特异性结合SSTR5阳性肿瘤细胞并增强化疗药物递送效率。

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**检索建议**:

1. 在PubMed中使用关键词:**SSTR5 antibody AND (neuroendocrine tumor OR imaging)**

2. 关注期刊:*Endocrine-Related Cancer*, *Molecular Pharmaceutics*

3. 常用抗体品牌:如Abcam、Santa Cruz的产品文献(官网Technical Documents版块)

       

背景信息

Somatostatin receptor subtype 5 (SSTR5) is a G protein-coupled receptor (GPCR) that binds somatostatin and its analogs, playing a key role in regulating hormone secretion, cell proliferation, and neurotransmission. It is one of five SSTR subtypes (SSTR1-5) with distinct tissue distributions and signaling pathways. SSTR5 is prominently expressed in neuroendocrine tissues, the pituitary gland, pancreas, and certain cancers, including neuroendocrine tumors (NETs), breast cancer, and prostate cancer.

SSTR5 antibodies are immunological tools designed to detect and quantify SSTR5 expression in research and diagnostics. They are widely used in techniques like immunohistochemistry (IHC), Western blotting, and flow cytometry to study SSTR5's role in disease mechanisms, particularly in tumors that overexpress this receptor. Clinically, SSTR5 is a therapeutic target; its antibodies aid in identifying patients eligible for somatostatin analog therapies (e.g., octreotide) or peptide receptor radionuclide therapy (PRRT).

Research on SSTR5 antibodies also explores their utility in understanding receptor internalization, dimerization, and cross-talk with other signaling pathways. Challenges include ensuring antibody specificity due to structural similarities among SSTR subtypes. Recent advances in monoclonal antibody development have improved targeting precision, supporting both basic research and translational applications in oncology and endocrinology.

       
SSTR5抗体;SSTR5;SSTR5 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。

成立日期 (2年)
注册资本 50万(元)
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,化学试剂

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