马来酸奥拉替尼；奥拉替尼；Oclacitinib Maleate；1208319-27-0 新品

产品描述

等级：活性药物成分（API）

化学名称：n-甲基-4-（甲基- 3h -吡咯[2,3-d]嘧啶-4-氨基）-反式-(2Z)-2-丁烯二酸酯（1:1）环己甲磺酰胺

分子式：C19H27N5O6S

分子量：453.513

规范：按照ChP/USP/EP建立企业标准

外观:粉

总杂质：不大于2.0%

纯度：不低于98%

残留溶剂：完全符合ICH Q3C要求

致突变杂质：完全符合ICH M8

亚硝胺评估：可用

粒度：可根据客户要求进行普通级或研磨/筛分。

储存方法：室温

生产能力：商用

标准包装：1kg/袋，5kg/袋，或根据客户要求

产品用途

奥克拉替尼被标记为治疗狗过敏引起的特应性皮炎和瘙痒（瘙痒），尽管它也被用于减少跳蚤感染引起的瘙痒和皮炎。它被认为对狗非常有效，并且至少在短期内使用是安全的。起初其疗效与强的松龙相当，虽然奥克拉替尼在短期内对瘙痒和皮炎更有效，但长期安全性尚不清楚。人们发现它比环孢素起效更快，引起的胃肠道问题也更少。虽然短期内是安全的，但奥克拉替尼的长期安全性尚不清楚。虽然有些人说它只对急性发痒最好，但其他人声称它对慢性特应性皮炎也有用。

联系方式

四川青木制药有限公司

四川省眉山市东坡区经济开发区东区顺江大道南段55号

国际营销部(International):

Email: sales@eastonpharma.cn 

Tel: 028-87827187

国内营销部(Mainland)：

李经理 13880480517   

杨经理 15982276454

Product Description

Grade: Active Pharmaceutical Ingredient(API)

Chemical Name: Cyclohexanemethanesulfonamide, N-methyl-4-(methyl-3H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-, trans-(2Z)-2-butenedioate (1:1)

Molecular Formula: C19H27N5O6S

Molecular Weight: 453.513

Specification: Enterprise Standard established according to ChP/USP/EP

Appearance: Powder

Total impurities: not more than 2.0%

Purity: not less than 98%

Residual Solvents: fully comply with ICH Q3C

Mutagenic impurities: fully comply with ICH M8

Nitrosamine assessment: available

Particle size: regular grade or milling/sieving according to customer’s requirement.

Storage: Room temperature

Production capacity: Commercial

Standard Package: 1kg/bag, 5kg/bag, or according to the customer’s requirement

Applications 

Oclacitinib is labeled to treat atopic dermatitis and itchiness (pruritus) caused by allergies in dogs, though it has also been used to reduce the itchiness and dermatitis caused by flea infestations. It is considered to be highly effective in dogs and has been established as safe for at least short-term use. Its efficacy equals that of prednisolone at first, though oclacitinib has been found to be more effective in the short term in terms of itchiness and dermatitis, long-term safety is unknown. It has been found to have a faster onset and cause fewer gastrointestinal issues than cyclosporine. While safe in the short term, oclacitinib’s long-term safety is unknown. While some say it is best only for acute flares of itchiness, others claim that it is also useful in chronic atopic dermatitis.

Contact Information

Sichuan Qingmu Pharmaceutical Co., Ltd.

Add: No. 55, South Shunjiang Avenue, East Economic Development Zone, Dongpo District, Meishan City, Sichuan, 620036, China

International Marketing Department: 

Email: sales@eastonpharma.cn 

Tel: 0086-28-87827187