重组人Arginase 1/ARG1蛋白-ACROBiosystems百普赛斯

Arginase 1产品信息

英文名称：Arginase-1

中文名称：精氨酸酶-1

靶点别称：ARG1

物种：Human

标签：His Tag

属性：Protein

标记：Unconjugated

表达区间及表达系统（Source）

Human Arginase 1, His Tag (AR1-H5228) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Lys 322 (Accession # NP_000036).

Predicted N-terminus: Met 1

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 35.8 kDa. The protein migrates as 35-38 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

精氨酸酶-1（ARG1）也被称为肝型精氨酸蛋白酶，I型精氨酸酯，属于精氨酸酶类。精氨酸酶-1/ARG1是一种含锰酶。该酶催化的反应为：精氨酸+H2O→鸟氨酸+尿素。它是尿素循环的最后一种酶。精氨酸酶-1/ARG1的缺陷是精氨酸血症（ARGIN）的原因。