重组小鼠AGR2蛋白-ACROBiosystems百普赛斯

Mouse AGR2 / AG-2 Protein, His Tag (MALS verified)

分子别名（Synonym）

AGR2,AG-2

表达区间及表达系统（Source）

Mouse AGR2, His Tag (AG2-M52H6) is expressed from human 293 cells (HEK293). It contains AA Lys 21 - Leu 175 (Accession # O88312-1).

Predicted N-terminus: Lys 21

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 19.8 kDa. The protein migrates as 23 kDa and 24 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

前梯度蛋白2（AGR2）是一种正常的内质网蛋白，具有两栖动物肢体再生和促进癌症转移两种重要的异常功能。这些正常的细胞内和异常的细胞外作用可归因于AGR2的多结构域结构。NMR结构显示AGR2由一个非结构化的N端区域和一个硫氧还蛋白折叠组成。