重组人IL20RA/IL-20Rα蛋白-ACROBiosystems百普赛斯

Human IL-20 R alpha Protein, His Tag (MALS & SPR verified)

分子别名（Synonym）

IL-20Rα，IL-20R1，IL20RA

表达区间及表达系统（Source）

Human IL-20 R alpha Protein, His Tag (ILA-H52H3) is expressed from human 293 cells (HEK293). It contains AA Val 30 - Lys 250 (Accession # Q9UHF4-1).

Predicted N-terminus: Val 30

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 27.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

IL-20 Rα（白细胞介素-20受体亚基α）与IL-20β亚基形成功能性异二聚体，并至少部分通过STAT3激活转导配体结合。细胞因子和受体的IL-20亚家族是更大的IL-10家族的成员，根据它们对共同受体亚基的利用、靶细胞谱的相似性和生物学功能将它们归为一类。该亚家族由细胞因子IL-19、IL-20、IL-22、IL-24和IL-26以及受体IL-20RA、IL-20RB、IL-10RB和IL-22RA1组成。