重组人AMIGO2蛋白-ACROBiosystems百普赛斯

Human AMIGO2 Protein, His Tag

分子别名（Synonym）

AMIGO2

表达区间及表达系统（Source）

Human AMIGO2, His Tag (AM2-H52H5) is expressed from human 293 cells (HEK293). It contains AA Val 31 - Thr 398 (Accession # Q86SJ2-1).

Predicted N-terminus: Val 31

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 43.5 kDa. The protein migrates as 58-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

癌症是最常见的恶性肿瘤之一，肝是胃癌血行转移最常见的部位。AMIGO2是一种I型跨膜蛋白，与腺癌中的肿瘤细胞粘附有关；然而，其在GC中的重要性尚未确定。但更多的数据表明，AMIGO2是一种新型抗转移治疗方法的新靶点，旨在阻断转移性肿瘤球体的内聚力、存活率和粘附性。