重组人CXCL9蛋白-ACROBiosystems百普赛斯

CXCL9产品信息

英文名称：C-X-C motif chemokine 9

中文名称：C-C基序趋化因子-9

靶点别称：CXCL9

物种：Human

标签：His Tag

属性：Protein

标记：Unconjugated

表达区间及表达系统（Source）

Human CXCL9 Protein, His Tag (CX9-H51H3) is expressed from E. coli cells. It contains AA Thr 23 - Thr 125 (Accession # Q07325).

Predicted N-terminus: Met

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 20.7 kDa. The protein migrates as 17-20 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, 0.5 M NaCl, 0.5 M Arginine, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

CXCL9是一种属于CXC趋化因子家族的小细胞因子，也称为由γ干扰素（MIG）诱导的单因子。CXCL9是一种在免疫反应中起作用的趋化因子，它可以诱导趋化性，促进白细胞的分化和增殖，并导致组织外渗。CXCL9通过与CXCR3受体（如CTL、NK细胞、NKT细胞和巨噬细胞）结合来调节免疫细胞的迁移、分化和激活。CXCL9还参与Th1极化和IFN-γ反应。