重组人EDNRA蛋白-ACROBiosystems百普赛斯

EDNRA产品信息

英文名称：Endothelin receptor type A

中文名称：内皮素A受体

靶点别称：EDNRA

物种：Human

属性：Protein

标记：Unconjugated

表达区间及表达系统（Source）

Human EDNRA Full Length Protein-VLP (EDA-H52P8) is expressed from human 293 cells (HEK293). It contains AA Asp 21 - Asn 427 (Accession # P25101-1).

Predicted N-terminus: Asp 21

蛋白结构（Molecular Characterization）

The protein has a calculated MW of 48.6 kDa | 56.1 kDa.

Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.

The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

制剂（Formulation）

The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).

Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

运输（Shipping）

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储（Storage）

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

The product MUST be stored at -70°C or lower upon receipt;

-70°C for 12 months under sterile conditions.

背景（Background）

EDNRA是一种在强效和持久的血管收缩中起作用的蛋白肽。这种受体与鸟嘌呤核苷酸结合（G）蛋白结合，这种偶联激活磷脂酰肌醇钙链。