大鼠Clec4b2蛋白-ACROBiosystems百普赛斯

Rat Clec4b2 Protein, His Tag

表达区间及表达系统（Source）

Rat Clec4b2 Protein, His Tag (CLB-R5246) is expressed from human 293 cells (HEK293). It contains AA Gln 42 - Leu 208 (Accession # F1M7G4-1).

Predicted N-terminus: His

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 21.6 kDa. The protein migrates as 27-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

CLEC4B2（C型凝集素结构域家族4，成员b2），也称为树突状细胞免疫活化受体1（DCAR1）和抗原呈递细胞凝集素样受体A1（APLRA1），是一种属于细胞表面C型凝集素域家族的II型膜蛋白。CLEC4B2在宿主防御中可能扮演第二个角色。Clec4b2是免疫系统细胞上的一种功能性受体，为CLR调节免疫反应提供了进一步的见解。CLEC4B2是对真菌感染和损伤的先天免疫反应所特别需要的，并且将这种GPCR放置在秀丽隐杆线虫表皮中先天免疫识别和信号传导的任何其他已知成分的上游。