单克隆抗Eribulin抗体-ACROBiosystems百普赛斯

Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1F5)

抗体来源（Source）

Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1F5) is a Rabbit monoclonal antibody recombinantly expressed from HEK293 cells.

克隆号（Clone）

1M1F5

种属（Species）

Rabbit

亚型（Isotype）

Rabbit IgG | Rabbit Kappa

抗体类型（Antibody Type）

Recombinant Monoclonal

种属反应性（Reactivity）

Chemical

特异性（Specificity）

This product is a specific antibody specifically reacts with Eribulin.

应用（Application）

纯度（Purity）

>95% as determined by SDS-PAGE.

纯化（Purification）

Protein A purified/ Protein G purified

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

Eribulin是大环聚醚盐球粒蛋白B的合成类似物，最初从亚洲海绵Halichondia okadai中分离出来。Eribulin特异性结合微管（+）端的β-微管蛋白亚基，有效抑制形成的微管的伸长，同时对微管解聚几乎没有影响。Eribulin强大的抗有丝分裂活性和对肿瘤生物学的非有丝分裂作用使其成为研究ADC MTA有效载荷的有趣候选者。