重组人FABP3蛋白-ACROBiosystems百普赛斯

Human FABP3 / H-FABP Protein, His Tag

分子别名（Synonym）

FABP3,H-FABP,FABP11,MDGI,M-FABP,hFABP,O-FABP

表达区间及表达系统（Source）

Human FABP3, His Tag (FA3-H5128) is expressed from E. coli cells. It contains AA Met 1 - Ala 133 (Accession # NP_004093).

Predicted N-terminus: Met 1

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 15.7 kDa. The protein migrates as 15-17 kDa under reducing (R) condition (SDS-PAGE).

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

脂肪酸结合蛋白3（FABP3）也称为心脏型脂肪酸结合蛋白质（H-FABP）、乳腺衍生生长抑制剂（MDGI）、肌肉脂肪酸结合蛋白酶（M-FABP）和FABP11，属于calycin超家族和脂肪酸结合酶（FABP）家族。FABP被认为在长链脂肪酸及其酰基辅酶a酯的细胞内运输中发挥作用。H-FABP/FABP3参与活性脂肪酸代谢，将脂肪酸从细胞膜运输到线粒体进行氧化。FABP3还可能通过在脂毒性条件下维持细胞中胰岛素依赖性Akt的激活来促进AS160磷酸化。