重组人CNTFRα蛋白-ACROBiosystems百普赛斯

CNTF R alpha产品信息

英文名称：Ciliary neurotrophic factor receptor

中文名称：睫状神经营养因子受体

靶点别称：CNTFR，CNTFRa，CNTFR-Alpha 

物种：Human

标签：His Tag

属性：Protein

标记：Unconjugated

表达区间及表达系统（Source）

Human CNTF R alpha, His Tag (CNR-H5225) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Pro 346 (Accession # AAH01492).

Predicted N-terminus: Gln 23

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 37.6 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

睫状神经营养因子受体亚基α（CNTFR或CNTFRα）属于I型细胞因子受体家族和3型亚家族。CNTFR包含两个纤维连接蛋白III型结构域和一个Ig样C2型（免疫球蛋白样）结构域。这种受体及其同源配体支持神经元的存活。该受体与白细胞介素-6受体关系最为密切。这种受体通过糖磷脂酰肌醇连接与细胞膜具有不寻常的连接。