重组人CD37蛋白-ACROBiosystems百普赛斯

CD37产品信息

英文名称：Leukocyte antigen CD37

中文名称：白细胞抗原CD37

靶点别称：CD37，TSPAN26，Tetraspanin-26

物种：Human

标签：His Tag/Fc Tag

属性：Protein

标记：FITC Labeled/Unconjugated

表达区间及表达系统（Source）

Human CD37, Fc Tag (CD7-H525a) is expressed from human 293 cells (HEK293). It contains AA Arg 112 - Asn 241 (Accession # P11049-1).

Predicted N-terminus: Arg 112

蛋白结构（Molecular Characterization）

This protein carries a human IgG1 Fc tag at the C-terminus.

The protein has a calculated MW of 41.3 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

白细胞抗原CD37（CD37）也被称为Tetraspanin-26（Tspan-26）和TSPAN26，TSPAN26是跨膜4超家族或Tetraspanin家族的成员。这些成员中的大多数是细胞表面蛋白，其特征是存在四个疏水结构域。CD37基因编码的蛋白质介导信号转导事件，这些事件在细胞发育、活化、生长和运动的调节中发挥作用。CD37是一种已知与整合素和其他跨膜4超家族蛋白复合的细胞表面糖蛋白。CD37可能在T细胞与B细胞的相互作用中发挥作用。