重组人CD160蛋白-ACROBiosystems百普赛斯

Human CD160 Protein, His Tag

分子别名（Synonym）

CD160,BY55,NK1,NK28

表达区间及表达系统（Source）

Human CD160, His Tag (BY5-H5229) is expressed from human 293 cells (HEK293). It contains AA Ile 27 - Ser 159 (Accession # O95971-1).

Predicted N-terminus: Ile 27

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 16.7 kDa. The protein migrates as 25-28 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

CD160抗原也被称为自然杀伤细胞受体BY55，是一种27kDa的糖蛋白，含有1个Ig样V型（免疫球蛋白样）结构域。其表达与外周血NK细胞和具有细胞溶解效应活性的CD8 T淋巴细胞密切相关。CD160在细胞表面表达为紧密二硫键连接的多聚体。在组织中，CD160在所有肠上皮内淋巴细胞上表达。CD160显示出与经典和非经典MHC I类分子结合的广泛特异性。当在血管内皮细胞上表达时，CD160传播抗血管生成信号并促进细胞凋亡。