重组人CCL27蛋白-ACROBiosystems百普赛斯

Human CCL27 Protein, His Tag

分子别名（Synonym）

ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27

表达区间及表达系统（Source）

Human CCL27 Protein, His Tag (CC7-H5143) is expressed from E. coli cells. It contains AA Phe 25 - Gly 112 (Accession # Q9Y4X3).

Predicted N-terminus: Met

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 12.2 kDa. The protein migrates as 11 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, 0.2 M Arginine, pH7.3 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

该基因是聚集在9号染色体p臂上的几个CC细胞因子基因之一。细胞因子是一个参与免疫调节和炎症过程的分泌蛋白家族。CC细胞因子是以两个相邻半胱氨酸为特征的蛋白质。该基因编码的蛋白质对皮肤相关记忆T淋巴细胞具有趋化性。这种细胞因子也可能在介导淋巴细胞归巢到皮肤部位中发挥作用。它特异性结合趋化因子受体10（CCR10）。对类似小鼠蛋白质的研究表明，这些蛋白质-受体相互作用在T细胞介导的皮肤炎症中起着关键作用。