重组人单胺氧化酶B（MAOB）蛋白-ACROBiosystems百普赛斯

MAOB产品信息

英文名称：Monoamine oxidase B

中文名称：单胺氧化酶B

靶点别称：MAOB

物种：Human

标签：His Tag

属性：Protein

标记：Unconjugated

表达区间及表达系统（Source）

Human MAOB, His Tag (MAB-H5547) is expressed from Baculovirus-Insect cells. It contains AA Ser 2 - Val 520 (Accession # P27338-1).

Predicted N-terminus: Met

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 60.6 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE).

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

This product is not suitable for cell based experiments due to cytotoxicity of DDM.

DDM and CHS are INDISPENSABLE to keep membrane protein soluble and active, under no circumastance should you remove DDM and CHS.

DDM/CHS buffer (DC-11) is sold separately and not included in protein, and please contact us if you need the buffer.

If glycerol is not compatible to your application, remove glycerol just before immediate experiment, and NEVER store glycerol-free protein solution.

Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

运输（Shipping）

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储（Storage）

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

The product MUST be stored at -70°C or lower upon receipt;

-70°C for 3 months under sterile conditions.

背景（Background）

B型单胺氧化酶（MAOB）是一种位于线粒体外膜的酶。它催化生物胺和外源胺的氧化脱氨基，在大脑中多巴胺的分解中起着重要作用。MAOB抑制剂可以减少多巴胺的代谢，目前临床上用于治疗帕金森病（PD）。