SHR-2042/GLP-1受体选择性激动剂多肽SHR-2042

Product Name： SHR-2042

CAS No.：N/A

Synonyms：GLP-1受体选择性激动剂多肽SHR-2042

Catalog No.：PYC-091

Description：SHR-2042 是 GLP-1 受体的选择性激动剂，其由39个氨基酸组成。SHR-2042 通过激活 GLP-1 受体，增强胰岛素分泌，抑制胰高血糖素分泌，从而改善血糖控制。其与 sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) 结合后，通过形成胶束促进单体化，提高了口服吸收效率。

SHR-2042 is a selective agonist of GLP-1 receptor, consisting of 39 amino acids. SHR-2042 improves blood glucose control by activating GLP-1 receptors, enhancing insulin secretion, and inhibiting glucagon secretion. After binding with sodium N - (8- [2-hydroxybenzyl] amino) caprylate (SNAC), it promotes monomerization by forming micelles, thereby improving oral absorption efficiency.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	H-{Aib}-EGTFTSDVSSYLEEEAAKEFIAWLVRGGPSSGAPPPS-{εK(C16 acid)}
Sequence(3-letter code)	His-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Glu-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-{εLys(C16 acid)}
Peptide Structure
Molecular Formula	C205H314N48O63
Molecular Weight	4458.97

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