基本信息 产品详情 公司简介 推荐产品
网站主页 CCND2, HUMAN, 重组蛋白 (HIS) CCND2, Human, 重组蛋白 (His)
  • CCND2, Human, 重组蛋白 (His)|TMPJ-00936|TargetMol

CCND2, Human, 重组蛋白 (His)|TMPJ-00936|TargetMol

CCND2 Protein, Human, Recombinant (His)
17400 1mg 起订
上海 更新日期:2024-09-30

TargetMol中国(陶术生物)

VIP1年
联系人:邵小姐
手机:15002134094 拨打
邮箱:marketing@targetmol.cn

产品详情:

中文名称:
CCND2, Human, 重组蛋白 (His)
英文名称:
CCND2 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
store at low temperature | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice.
产品类别:
抑制剂
货号:
TMPJ-00936

Product Introduction

Bioactivity

名称CCND2 Protein, Human, Recombinant (His)
描述CCND2,also known as G1/S-specific cyclin-D2,is a member of the highly conserved cyclin family. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 is involved in a number of fundamental biological processes such as phosphorylating and inhibiting members of the retinoblastoma (RB) protein family including RB1 and regulating the cell-cycle during G1/S transition. It is also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
存储条件store at low temperature | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice.
关键字CCND 2 | CCND-2
G1/S-specific cyclin-D2|||CCND2|TargetMol

公司简介

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿,致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区,已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库,以及多种类型的生化试剂产品,包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等,此外,我们还建设有CADD(计算机辅助药物设计)研究中心、药理实验室、药化合成平台三大技术中心,全方位满足客户的定制需求。 凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持,我们将有效帮助您缩短研发周期,取得更成功的结果。

成立日期 (12年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,天然产物,生物化工,化学试剂,生物技术服务

CCND2, Human, 重组蛋白 (His)相关厂家报价

内容声明
拨打电话 立即询价