Dios-Arg (trifluoroacetate salt)|T36359|TargetMol

Dios-Arg (trifluoroacetate salt)
1807353-31-6

￥2750 5mg 起订

￥4660 10mg 起订

￥812 1mg 起订

上海更新日期：2025-11-17

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产品详情:

中文名称：: Dios-Arg (trifluoroacetate salt)

英文名称：: Dios-Arg (trifluoroacetate salt)

CAS号：: 1807353-31-6

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

产品类别：: 抑制剂

货号：: T36359

Product Introduction

Bioactivity

名称	Dios-Arg (trifluoroacetate salt)
描述	Dios-Arg is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratio greater than or equal to 4. Dios-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence and absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the caveolae-mediated endocytosis inhibitor genistein . It has been used, coupled to 1,2-dioleoyl-sn-glycero-3-PE , to bind siRNA and plasmid DNA to form cationic lipid nanoparticles for intracellular transport. Dios-Arg is cytotoxic to H1299 and HeLa cells (IC50s = 83.5 and 74.1 μg/ml, respectively).
存储条件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度	DMSO : 30 mg/mL (32.89 mM), Sonication is recommended. PBS (pH 7.2) : 1 mg/mL (1.1 mM), Sonication is recommended. Ethanol : 30 mg/mL (32.89 mM), Sonication is recommended. DMF : 30 mg/mL (32.89 mM), Sonication is recommended.
关键字	Dios Arg (trifluoroacetate salt) \| DiosArg (trifluoroacetate salt) \| Dios-Arg
相关产品	Cholesterol \| DSPS \| 1,2-Distearoyl-sn-glycero-3-phosphorylcholine \| SM-102 \| Phosphatidylcholines,soya \| DPPC \| 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine \| 1,2-dioleoyl-sn-glycero-3-phosphocholine \| DODAP \| 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC \| ALC-0315 \| D-Lin-MC3-DMA

Dios-Arg (trifluoroacetate salt)|TargetMol

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

成立日期	(13年)
注册资本	566.265100万人民币
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年营业额	￥ 1亿以上
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主营行业	天然产物,生化试剂,分子生物学,分子砌块,生物技术服务

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