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网站主页 CD32A, HUMAN, 重组蛋白 (R167, HIS) CD32A, Human, 重组蛋白 (R167, His)
  • CD32A, Human, 重组蛋白 (R167, His)|TMPJ-00446|TargetMol

CD32A, Human, 重组蛋白 (R167, His)|TMPJ-00446|TargetMol

CD32A Protein, Human, Recombinant (R167, His)
￥17400 1mg 起订
上海 更新日期：2024-12-02

TargetMol中国（陶术生物）

VIP1年
联系人：邵小姐
手机：15002134094 拨打
邮箱：marketing@targetmol.cn

产品详情:

中文名称：
CD32A, Human, 重组蛋白 (R167, His)
英文名称：
CD32A Protein, Human, Recombinant (R167, His)
品牌：
TargetMol
产地：
美国
保存条件：
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice.
产品类别：
抑制剂
货号：
TMPJ-00446

Product Introduction

Bioactivity

名称CD32A Protein, Human, Recombinant (R167, His)
描述Receptors for the Fc region of IgG (FcγR) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Human FcγRs are divided into three classes designated FcγRI (CD64), FcγRII (CD32), and FcγRIII (CD16), which generate multiple isoforms, are recognized. The activating­ type receptor either has or associates non­covalently with an accessory subunit that has an immunoreceptor tyrosine­based activation motif (ITAM) in its cytoplasmic domain. FcγRI binds IgG with high affinity and functions during early immune responses, whereas FcγRII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Three genes for human FcγRII (A, B, and C) and one for mouse (FcγRIIB), encoding type I transmembrane proteins with ITAM motifs (FcγRII A and C) or ITIM motifs (FcγRIIB) in their cytoplasmic domains, have been identified. Human CD32, also known as Low affinity immunoglobulin γ Fc region receptor II-a (IgG Fc receptor II-a), FcγRII A or FCGR2A Protein, is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. Associated with an ITAM-bearing adapter subunit, FcRγ, CD32a (FcγRII A) delivers an activating signal upon ligand binding, and results in the initiation of inflammatory responses including cytolysis, phagocytosis, degranulation, and cytokine production. The responses can be modulated by signals from the co-expressed inhibitory receptors such as Fcγ RII B, and the strength of the signal is dependent on the ratio of expression of the activating and inhibitory receptors.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice.
关键字IGFR 2 | CD 32 | IGFR-2 | FCG 2 | FCG-2 | CD-32
FcRII-a|||IGFR2|||Low Affinity Immunoglobulin Gamma Fc Region Receptor II-a|||Fc-Gamma RII-a|||FCGR2A1|||Fc-γ RII-a|||FCGR2A|||CDw32|||FCG2|||Fc-Gamma-RIIa|||CD32|||Low Affinity Immunoglobulin γ Fc Region Receptor II-a|||IgG Fc receptor II-a|||Fc-γ-RIIa|TargetMol

公司简介

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。 凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

成立日期 (12年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,天然产物,生物化工,化学试剂,生物技术服务

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