Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
产品类别:
抑制剂
货号:
T37945
Product Introduction
Bioactivity
名称
Bimatoprost methyl ester
描述
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
存储条件
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度
PBS (pH 7.2) : 0.25 mg/mL (0.62 mM), Sonication is recommended. Acetonitrile : 3 mg/mL (7.45 mM), Sonication is recommended. Ethanol : 50 mg/mL (124.21 mM), Sonication is recommended. DMSO : 25 mg/mL (62.11 mM), Sonication is recommended. DMF : 25 mg/mL (62.11 mM), Sonication is recommended.