酒石酸艾芬地尔|T1186|TargetMol

Ifenprodil Tartrate
23210-58-4

￥197 10mg 起订

￥355 25mg 起订

￥587 50mg 起订

上海更新日期：2024-09-29

TargetMol中国（陶术生物）

VIP3年

联系人：邵小姐

手机：4008200310 拨打

邮箱：marketing@tsbiochem.com

产品详情:

中文名称：: 酒石酸艾芬地尔

英文名称：: Ifenprodil Tartrate

CAS号：: 23210-58-4

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 99.7%

产品类别：: 抑制剂

货号：: T1186

Product Introduction

Bioactivity

Name	Ifenprodil Tartrate
Description	Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
Kinase Assay	In vitro biochemical and pharmacological assaysinhibition studies with recombinant human COX-1 and COX-2: Microsomal preparations of recombinant human COX-1 and COX-2 are prepared from a vaccinia virus-COS-7 cell expression system. Recombinant human COX-1 and COX-2 are expressed in baculovirus-Sf9 cells, and enzymes are purified. Enzymatic activity is monitored continuously by either a fluorescence assay measuring the appearance of the oxidized form of the reducing agent cosubstrate homovanillic acid or by oxygen consumption. The HPLC assay for the assessment of inhibition of purified COX-1 by Rofecoxib with 0.1 μM arachidonic acid substrate concentration, the determination of the stoichiometry of the complex between COX-2 and Rofecoxib, the dissociation rate constant of the enzyme-inhibitor complex by recovery of enzymatic activity, and the recovery of intact Rofecoxib from that complex are all performed as described previously. The solvent system for the HPLC analysis of Rofecoxib is 15:85 MeOH/aqueous potassium phosphate (1 g/liter), with elution by a linear gradient of 15 to 75% MeOH over 25 minutes with detection at 275 nm on a Novapak C18 column.
In vivo	Ifenprodil抑制NMDA（10 μM）和NMDA（100 μM）诱发的电流,IC 50值分别为0.88 μM和0.17μ。在大鼠皮质神经元中,Ifenprodil（10 μM）抑制大部分的NMDA受体诱发的电流。
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 45 mg/mL (112.36 mM) Ethanol : 58 mg/mL (107.7 mM) H2O : 9 mg/mL (11.23 mM)
Keywords	KcsA \| inhibit \| Ifenprodil Tartrate \| vasodilator \| iGluR \| current \| Ionotropic glutamate receptors \| Ifenprodil \| NR1A \| Inhibitor \| NMDA \| Potassium Channel \| cerebral \| NR2B
Inhibitors Related	glycine \| L-Glutamic acid \| Cloperastine hydrochloride \| L-Glutamic acid monosodium salt \| 2,2,2-Trichloroethanol \| Minoxidil sulfate \| Indapamide \| Riluzole \| Halothane
Related Compound Libraries	Neuroprotective Compound Library \| Bioactive Compound Library \| Anti-Cancer Active Compound Library \| Bioactive Compounds Library Max \| Ion Channel Targeted Library \| Anti-Neurodegenerative Disease Compound Library \| Membrane Protein-targeted Compound Library \| Pain-Related Compound Library \| Anti-Cancer Clinical Compound Library \| Anti-Cancer Drug Library

酒石酸艾芬地尔|TargetMol

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

成立日期	(12年)
注册资本	566.265100万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,工厂,试剂,定制,服务
主营行业	天然产物,生化试剂,分子生物学,分子砌块,生物技术服务

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