基本信息 产品详情 公司简介 推荐产品
网站主页 化工产品目录 生物化工 生化试剂 激动剂抑制剂 339539-92-3 富马酸阿拉莫林
  • 富马酸阿拉莫林|T10319L|TargetMol

富马酸阿拉莫林|T10319L|TargetMol

Anamorelin Fumarate
339539-92-3
19500 100mg 起订
15300 50mg 起订
11700 25mg 起订
上海 更新日期:2025-11-17

TargetMol中国(陶术生物)

VIP4年
联系人:邵小姐
手机:4008200310 拨打
邮箱:marketing@tsbiochem.com

产品详情:

中文名称:
富马酸阿拉莫林
英文名称:
Anamorelin Fumarate
CAS号:
339539-92-3
品牌:
TargetMol
产地:
美国
保存条件:
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
产品类别:
抑制剂
货号:
T10319L

Product Introduction

Bioactivity

名称Anamorelin Fumarate
描述Anamorelin Fumarate is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).
体外活性No significant antagonist activity is observed with Anamorelin at concentrations of up to 1,000 nM. In the binding experiments, Anamorelin binds to the ghrelin receptor with a binding affinity constant (Ki) of 0.70 nM. In the competition assay with radiolabeled ibutamoren (another ghrelin receptor agonist), Anamorelin is also found to bind with high affinity to the ghrelin receptor (IC50: 0.69 nM). In rat pituitary cells incubated with Anamorelin, there is a dose-dependent stimulatory effect on GH release and the potency (EC50) is 1.5 nM. Anamorelin is screened for activity against a set of over 100 receptors, ion channels, transporters, and enzymes. Anamorelin demonstrates binding to the tachykinin neurokinin 2 (NK2) site (IC50: 0.021 μM); however, a subsequent NK2 functional assay demonstrates no functional activity.
体内活性In rats, Anamorelin at an oral dose of 3, 10, or 30 mg/kg once daily significantly increases both food intake and body weight from Day 2 to Day 7 of treatment compared with the vehicle control. The cumulative change in food intake and weight gain increases dose-dependently, and these changes are significant at all dose levels compared to the control. Administration of Anamorelin at a single oral dose of 3, 10, or 30 mg/kg induces a dose-dependent increase in plasma GH levels and GH AUC0-6h in rats.
存储条件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
关键字RC-1291 Fumarate | RC 1291 Fumarate | ONO7643 Fumarate | ONO 7643 Fumarate | ghrelin receptor | Anamorelin Fumarate
相关产品Human growth hormone-releasing factor acetate | TM-N1324 | Obestatin (rat) acetate | TC-G-1008 | Anamorelin | Ibutamoren | CJC-1295 acetate(863288-34-0 free base) | Ibutamoren Mesylate | YIL 781 | AnaMorelin hydrochloride | L-692429 | Cortistatin-8 acetate
富马酸阿拉莫林|||RC1291 Fumarate|||ONO-7643 Fumarate|TargetMol

公司简介

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿,致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区,已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库,以及多种类型的生化试剂产品,包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等,此外,我们还建设有CADD(计算机辅助药物设计)研究中心、药理实验室、药化合成平台三大技术中心,全方位满足客户的定制需求。 凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持,我们将有效帮助您缩短研发周期,取得更成功的结果。

成立日期 (13年)
注册资本 566.265100万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生化试剂,分子生物学,分子砌块,生物技术服务

富马酸阿拉莫林相关厂家报价

内容声明
拨打电话 立即询价