COQ7-IN-1|T35861|TargetMol

COQ7-IN-1
2579696-72-1

￥869 5mg 起订

￥497 2mg 起订

上海更新日期：2025-11-17

TargetMol中国（陶术生物）

VIP2年

联系人：邵小姐

手机：15002134094 拨打

邮箱：marketing@targetmol.cn

产品详情:

中文名称：: COQ7-IN-1

英文名称：: COQ7-IN-1

CAS号：: 2579696-72-1

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

产品类别：: 抑制剂

货号：: T35861

Product Introduction

Bioactivity

名称	COQ7-IN-1
描述	COQ7-IN-1 is a powerful inhibitor of human coenzyme Q (COQ7), effectively disrupting the synthesis of ubiquinone (UQ) in the body. Notably, COQ7-IN-1 does not disrupt the natural growth of human normal culture cells. This compound proves valuable for investigating the equilibrium between two pathways of UQ supplementation: de novo UQ synthesis and extracellular UQ uptake[1].
体外活性	COQ7-IN-1 (Compound 8; 0-30 μM; for 4 days) inhibits WI-38 cells growth with a GI50 of 19.0 μM. COQ7-IN-1 weakly inhibits C3A cells growth with GI50 of 9.0±1.1 μM. COQ7-IN-1 does not limit C3A cell survival through inhibiting aerobic respiration or increasing oxidative stress[1].COQ7 converts demethoxy-UQ (DMQ) to demethyl-UQ (DMeQ), and then converted to UQ by COQ3. Cells under COQ7 deficiency are unable to produce UQ, and consequently accumulate DMQ. DMQ10 and UQ10 contents in each culture well are 13.2 and 12.2 ng/well for COQ7-IN-1 (10 μM; for 2 days) cultured with HeLa cells. DMQ10 content of COQ7-IN-1 in HeLa cells is 52.0%[1].
存储条件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度	10% DMSO+90% Corn Oil : 3.3 mg/mL (12.15 mM), Sonication is recommended. DMSO : 100 mg/mL (368.05 mM), Sonication is recommended.
关键字	COQ-7-IN-1 \| COQ7IN1 \| COQ7 IN 1
相关产品	L-Histidine \| Sodium Molybdate \| (-)-Epigallocatechin Gallate \| Glibenclamide \| Ciprofloxacin monohydrochloride \| Rotenone \| Imeglimin hydrochloride \| 1-Hexanol \| 4-Pentenoic acid \| Tolfenpyrad \| DL-Carnitine \| Ciprofloxacin hydrochloride monohydrate

COQ7-IN-1|TargetMol

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

成立日期	(13年)
注册资本	589.8595万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,工厂,试剂,定制,服务
主营行业	中间体,天然产物,生物化工,化学试剂,生物技术服务

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