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网站主页 EDA2R, MOUSE, 重组蛋白 (HIS) EDA2R, Mouse, 重组蛋白 (His)
  • EDA2R, Mouse, 重组蛋白 (His)|TMPJ-01211|TargetMol

EDA2R, Mouse, 重组蛋白 (His)|TMPJ-01211|TargetMol

EDA2R Protein, Mouse, Recombinant (His)
14200 1mg 起订
上海 更新日期:2024-09-29

TargetMol中国(陶术生物)

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联系人:邵小姐
手机:15002134094 拨打
邮箱:marketing@targetmol.cn

产品详情:

中文名称:
EDA2R, Mouse, 重组蛋白 (His)
英文名称:
EDA2R Protein, Mouse, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice.
产品类别:
抑制剂
货号:
TMPJ-01211

Product Introduction

Bioactivity

名称EDA2R Protein, Mouse, Recombinant (His)
描述Tumor necrosis factor receptor superfamily member 27, also known as XEDAR and EDA2R, is a type III transmembrane protein of the TNFR superfamily. EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. EDA2R is widely expressed, notably in embryonic basal epidermal cells and maturing hair follicles. Even though it does not contain a cytoplasmic death domain, EDA2R can associate with Fas and induce EDA‑A2 dependent apoptosis. Its transcription is directly induced by p53, and it mediated cell death is p53 dependent. it is down‑regulated in breast, colon, and lung cancers, particularly in cases with p53 mutations. It also plays a role in EDA‑A2 induced skeletal muscle degeneration and osteoblast differentiation. Mutations in the EDA gene are associated with the X-linked form of Hypohidrotic Ectodermal Dysplasia (HED), a disease typically characterized by abnormal hair, teeth and sweat glands.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice.
关键字TNFRSF 27 | EDAR 2 | TNFRSF-27 | EDAR-2
EDA-A2R|||Tumor necrosis factor receptor superfamily member XEDAR|||EDA-A2 receptor|||XEDAR|||EDAR2|||X-linked ectodysplasin-A2 receptor|||TNFRSF27|||Ectodysplasin A2 receptor|||Tumor necrosis factor receptor superfamily member 27|||EDAA2R|TargetMol

公司简介

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿,致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区,已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库,以及多种类型的生化试剂产品,包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等,此外,我们还建设有CADD(计算机辅助药物设计)研究中心、药理实验室、药化合成平台三大技术中心,全方位满足客户的定制需求。 凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持,我们将有效帮助您缩短研发周期,取得更成功的结果。

成立日期 (12年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,天然产物,生物化工,化学试剂,生物技术服务

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