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网站主页 CADM1, MOUSE, 重组蛋白 (HFC) CADM1, Mouse, 重组蛋白 (hFc)
  • CADM1, Mouse, 重组蛋白 (hFc)|TMPJ-00281|TargetMol

CADM1, Mouse, 重组蛋白 (hFc)|TMPJ-00281|TargetMol

CADM1 Protein, Mouse, Recombinant (hFc)
17400 1mg 起订
上海 更新日期:2024-12-02

TargetMol中国(陶术生物)

VIP1年
联系人:邵小姐
手机:15002134094 拨打
邮箱:marketing@targetmol.cn

产品详情:

中文名称:
CADM1, Mouse, 重组蛋白 (hFc)
英文名称:
CADM1 Protein, Mouse, Recombinant (hFc)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice.
产品类别:
抑制剂
货号:
TMPJ-00281

Product Introduction

Bioactivity

名称CADM1 Protein, Mouse, Recombinant (hFc)
描述Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. CADM1 may contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, it may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. The protein acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly. It may be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. CADM1 may play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice.
关键字NECL 2 | NECL2 | TSLC 1 | TSLC1
IgSF4|||NECL-2|||Nectin-like protein 2|||Immunoglobulin superfamily member 4|||TSLC-1|||Cell adhesion molecule 1|||Tumor suppressor in lung cancer 1|||Synaptic cell adhesion molecule|||SynCAM|TargetMol

公司简介

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿,致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区,已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库,以及多种类型的生化试剂产品,包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等,此外,我们还建设有CADD(计算机辅助药物设计)研究中心、药理实验室、药化合成平台三大技术中心,全方位满足客户的定制需求。 凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持,我们将有效帮助您缩短研发周期,取得更成功的结果。

成立日期 (12年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,天然产物,生物化工,化学试剂,生物技术服务

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