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网站主页 LAMP1, MOUSE, 重组蛋白 (HIS) LAMP1, Mouse, 重组蛋白 (His)
  • LAMP1, Mouse, 重组蛋白 (His)|TMPJ-00837|TargetMol

LAMP1, Mouse, 重组蛋白 (His)|TMPJ-00837|TargetMol

LAMP1 Protein, Mouse, Recombinant (His)
14200 1mg 起订
上海 更新日期:2025-11-17

TargetMol中国(陶术生物)

VIP2年
联系人:邵小姐
手机:15002134094 拨打
邮箱:marketing@targetmol.cn

产品详情:

中文名称:
LAMP1, Mouse, 重组蛋白 (His)
英文名称:
LAMP1 Protein, Mouse, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
store at low temperature | Shipping with blue ice/Shipping at ambient temperature.
产品类别:
抑制剂
货号:
TMPJ-00837

Product Introduction

Bioactivity

名称LAMP1 Protein, Mouse, Recombinant (His)
描述Lysosomal associated membrane protein 1 (LAMP1) is an approximately 120 kDa transmembrane glycoprotein that is a major protein component of lysosomal membranes. Mature mouse LAMP1 consists of a 346 amino acid (aa) intralumenal domain (ECD), a 24 aa transmembrane segment, and a 12 aa cytoplasmic tail. Its lumenal domain is organized into two heavily N-glycosylated regions separated by a Ser/Pro-rich linker that carries a minor amount of O-linked glycosylation. Within the lumenal domain, mouse LAMP1 shares approximately 64% and 82% aa sequence identity with human and rat LAMP1, respectively. The sorting of LAMP1 to lysosomes relies on a tyrosine motif in the cytoplasmic tail. In cytotoxic T cells and mast cells, LAMP1 is expressed in the membranes of intracellular granules that contain effector molecules such as perforin, granzymes, eicosanoids, and histamine. A glycoform of LAMP1 known as M150 is expressed on the surface of activated macrophages where it promotes T cell co-stimulation and a Th1 biased immune response. Exposure of epithelial cells to pathogenic Neisseria bacteria induces the redistribution of LAMP1 to the cell surface where it can be cleaved by the Neisseria IgA1 protease.
存储条件store at low temperature | Shipping with blue ice/Shipping at ambient temperature.
关键字LGP120 | LGP 120 | LAMP1 | LAMP 1
P2B|||Lysosome-associated membrane protein 1|||Lysosome-associated membrane glycoprotein 1|||Lysosomal membrane glycoprotein A|||LGP-A|||LGP-120|||LAMP-1|||CD107a|||CD107 antigen-like family member A|||120 kDa lysosomal membrane glycoprotein|TargetMol

公司简介

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿,致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区,已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库,以及多种类型的生化试剂产品,包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等,此外,我们还建设有CADD(计算机辅助药物设计)研究中心、药理实验室、药化合成平台三大技术中心,全方位满足客户的定制需求。 凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持,我们将有效帮助您缩短研发周期,取得更成功的结果。

成立日期 (13年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,天然产物,生物化工,化学试剂,生物技术服务

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