(-)-对溴四咪唑草酸盐|T6353|TargetMol

(-)-p-Bromotetramisole Oxalate
62284-79-1

￥117 2mg 起订

￥178 5mg 起订

￥298 10mg 起订

上海更新日期：2024-09-29

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产品详情:

中文名称：: (-)-对溴四咪唑草酸盐

英文名称：: (-)-p-Bromotetramisole Oxalate

CAS号：: 62284-79-1

品牌：: TargetMol

产地：: 美国

保存条件：: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 99.74%

产品类别：: 抑制剂

货号：: T6353

Product Introduction

Bioactivity

Name	(-)-p-Bromotetramisole Oxalate
Description	(-)-p-Bromotetramisole Oxalate (6-Bromolevamisole oxalate) is a potent and non-specific inhibitor of alkaline phosphatase.
In vitro	Aurora A Inhibitor I is a 2,4-dianilinopyrimidine that selectively and potently inhibits Aurora A. Aurora A Inhibitor I effectively inhibits the proliferation of HCT116 and HT29 cells, with IC50 of 190 nM and 2.9 μM, respectively. The Aurora A selectivity of Aurora A Inhibitor I against Aurora B depends on a single amino acid (Thr217) of Aurora A. [1] In KCL-22 cells, Aurora A Inhibitor I (1-5 μM) increases G2/M cell fraction, induces histone H3 serine 10 phosphorylation, and suppresses mitotic Aurora A autophosphorylation on Thr288. Aurora A Inhibitor I (0.5-5 μM) also suppresses cell proliferation in KCL-22 cells, as well as BCR-ABL-negative leukemia cell lines KG-1 and HL-60. Aurora A Inhibitor I effectively induces apoptosis in KCL-22 cells at 5 μM. [2] In a recent study, Aurora A Inhibitor I is also found to inhibit cell growth of HCT116, HT29, and HeLa cells, with IC50 of 377.6 nM, 5.6 μM, and 416 nM. [3]
Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	H2O : 28 mg/mL (75 mM) Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 60 mg/mL (160.76 mM)
Keywords	L-p-Bromotetramisole Oxalate \| ( ) p Bromotetramisole Oxalate \| inhibit \| Phosphatase \| Inhibitor \| ()pBromotetramisole Oxalate \| 6-Bromolevamisole \| p-Bromolevamisole Oxalate \| p-Bromotetramisole Oxalate \| 6-Bromolevamisole Oxalate
Inhibitors Related	Sodium orthovanadate \| Stearic acid \| Tartaric acid disodium dihydrate \| PTP1B-IN-22 \| Cyclosporine \| Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride \| L-Ascorbic acid 2-phosphate magnesium \| β-Glycerophosphate disodium salt pentahydrate \| Tetramisole hydrochloride \| Trimyristin
Related Compound Libraries	Inhibitor Library \| Lipid Metabolism Compound Library \| Bioactive Compound Library \| Bioactive Compounds Library Max \| Phosphatase Inhibitor Library \| NO PAINS Compound Library \| Glycometabolism Compound Library \| Anti-Metabolism Disease Compound Library \| Target-Focused Phenotypic Screening Library

L-p-Bromotetramisole oxalate|||6-Bromolevamisole oxalate|||(-)-对溴四咪唑草酸盐|||(-)-p-Bromolevamisole oxalate|TargetMol

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

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