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网站主页 1-[(4-甲基磺酰基)苯基]-3-三氟甲基-5-(4-氟苯基)吡唑 化合物 SC 58125
  • 化合物 SC 58125|T23333|TargetMol

化合物 SC 58125|T23333|TargetMol

SC-58125
162054-19-5
147 1mg 起订
198 2mg 起订
347 5mg 起订
上海 更新日期:2024-09-29

TargetMol中国(陶术生物)

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产品详情:

中文名称:
化合物 SC 58125
英文名称:
SC-58125
CAS号:
162054-19-5
品牌:
TargetMol
产地:
美国
保存条件:
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
纯度规格:
99.81%
产品类别:
抑制剂
货号:
T23333

Product Introduction

Bioactivity

NameSC-58125
DescriptionSC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor, with an IC50 of 0.04 μM. SC-58125 exhibits antitumor activity in vitro and in vivo, and it also can inhibit edema at the inflammatory site and is analgesic
In vitroSC-58125 treatment on the growth of human colon carcinoma cells in nude mice.?Delaying treatment by 2, 4, or 7 weeks following implantation of the carcinoma cells resulted in a significant inhibition of tumor growth.?Furthermore, short-term (48 hours) treatment with SC-58125 was sufficient to attenuate tumor growth for up to 15 days.?SC-58125 treatment did not alter the rate at which cells underwent apoptosis, but did result in a delayed progression through the cell cycle at the G(2)/M transition.?Accordingly, p34(cdc2) protein levels and activity were decreased following SC-58125 treatment.SC-58125 primarily exerts a cytostatic effect in vivo, which is likely to be mediated through inhibition of progression through the G(2)/M phase of the cell cycle
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 9 mg/mL (23.42 mM)
KeywordsSC58125 | Cyclooxygenase | cancer | COX | Inhibitor | inflammatory | SC-58125 | antitumor | COX-2 | edema | inhibit
Inhibitors RelatedTrometamol | Revaprazan hydrochloride | 5-Aminosalicylic Acid | Ibuprofen | Paradol | Glafenine | trans-Cinnamaldehyde | Acetaminophen | Indomethacin sodium hydrate | Diclofenac Potassium | Salicylamide | Diclofenac sodium
Related Compound LibrariesInhibitor Library | Anti-Cancer Active Compound Library | Bioactive Compound Library | Bioactive Compounds Library Max | Anti-Pancreatic Cancer Compound Library | Anti-Colorectal Cancer Compound Library | Neuronal Signaling Compound Library | Anti-Aging Compound Library | Pain-Related Compound Library | Anti-Prostate Cancer Compound Library
SC 58125|||1-[(4-甲基磺酰基)苯基]-3-三氟甲基-5-(4-氟苯基)吡唑|TargetMol

公司简介

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿,致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区,已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库,以及多种类型的生化试剂产品,包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等,此外,我们还建设有CADD(计算机辅助药物设计)研究中心、药理实验室、药化合成平台三大技术中心,全方位满足客户的定制需求。 凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持,我们将有效帮助您缩短研发周期,取得更成功的结果。

成立日期 (12年)
注册资本 566.265100万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生化试剂,分子生物学,分子砌块,生物技术服务

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