Siglec-5, Human, 重组蛋白 (His & Flag & hFc)|TMPJ-00669|TargetMol

Siglec-5 Protein, Human, Recombinant (His & Flag & hFc)

￥12100 1mg 起订

上海更新日期：2026-05-08

TargetMol中国（陶术生物）

VIP3年

联系人：邵小姐

手机：15002134094 拨打

邮箱：marketing@targetmol.cn

产品详情:

中文名称：: Siglec-5, Human, 重组蛋白 (His & Flag & hFc)

英文名称：: Siglec-5 Protein, Human, Recombinant (His & Flag & hFc)

品牌：: TargetMol

产地：: 美国

保存条件：: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

产品类别：: 抑制剂

种属：: Human

表达系统：: HEK293 Cells

蛋白长度：: Glu17-Thr434

标签：: C-6xHis-Flag-hFc

货号：: T011|TMPJ-00669

Product Introduction

Bioactivity

名称	Siglec-5 Protein, Human, Recombinant (His & Flag & hFc)
描述	Human Siglec-5 are Itype(Igtype) lectins belonging to the Ig superfamily,They are characterized by an N terminal Ig-like V type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2 type domains. SIGLEC5 has also been designated CD170, they are expressed by monocytic or myeloid lineage cells, and also found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. SIGLEC5 are expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. Siglec5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. They are collectively referred to as CD33 related Siglecs. One remarkable feature of the CD33 related Siglecs is their differential expression pattern within the hematopoietic system This fact, together with the presence of two conserved immunoreceptor tyrosinebased inhibition motifs (ITIMs) in their cytoplasma tails, suggests that CD33 related Siglecs are involved in the regulation of cellular activation within the immune system.
存储条件	Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months
关键字	CD-170 \| CD 170

Siglec-5;Sialic acid-binding Ig-like lectin 5;Obesity-binding protein 2;OB-BP2;CD33 antigen-like 2;CD170;TargetMol

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

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