二苯基氯化碘盐|T7191|TargetMol

Diphenyleneiodonium chloride
4673-26-1

￥179 1mg 起订

￥398 5mg 起订

￥638 10mg 起订

上海更新日期：2024-09-24

TargetMol中国（陶术生物）

VIP12年

联系人：邵小姐

电话：021-021-33632979拨打

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邮箱：marketing@targetmol.com

产品详情:

中文名称：: 二苯基氯化碘盐

英文名称：: Diphenyleneiodonium chloride

CAS号：: 4673-26-1

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: ≥95%

产品类别：: 抑制剂

货号：: T7191

Product Introduction

Bioactivity

Name	Diphenyleneiodonium chloride
Description	Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity.
Cell Research	Whole-cell growth inhibition assays were used to screen and identify novel inhibitors. The hit compounds(Diphenyleneiodonium chloride) were tested for cytotoxicity against Vero cells to determine the selectivity index, and time-kill kinetics were determined against Mycobacterium fortuitum. The compound's ability to synergize with amikacin, ceftriaxone, ceftazidime and meropenem was determined using fractional inhibitory concentration indexes followed by its ability to decimate mycobacterial infections ex vivo[1].
In vitro	Diphenyleneiodonium chloride (DPIC), an NADPH/NADH oxidase inhibitor, as possessing potent antimicrobial activity against non-tuberculous mycobacteria.?DPIC exhibited concentration-dependent bactericidal activity against M. fortuitum and synergized with amikacin, ceftriaxone, ceftazidime and meropenem[1].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 6 mg/mL (19.07 mM)
Keywords	NADPH Oxidase \| Diphenyleneiodonium \| inhibit \| Reactive Oxygen Species \| NOX \| Diphenyleneiodonium Chloride \| Diphenyleneiodonium chloride \| TRP Channel \| Transient receptor potential channels \| Inhibitor
Inhibitors Related	Lycopene \| Sodium Thiocyanate \| Diallyl disulfide \| Glucosamine \| Metronidazole \| Apocynin \| Imeglimin hydrochloride \| L-Ascorbic acid \| Acetylcysteine \| Naringenin
Related Compound Libraries	Inhibitor Library \| Bioactive Compound Library \| Bioactive Compounds Library Max \| Metabolism Compound Library \| Highly Selective Inhibitor Library \| Anti-Aging Compound Library \| Ion Channel Targeted Library \| Membrane Protein-targeted Compound Library \| Anti-Neurodegenerative Disease Compound Library \| Pain-Related Compound Library

二苯基氯化碘盐|||DPI|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(12年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子