碘苷|T0863|TargetMol

Idoxuridine
54-42-2

￥172 500mg 起订

上海更新日期：2024-09-24

TargetMol中国（陶术生物）

VIP12年

联系人：邵小姐

电话：021-021-33632979拨打

手机：15002134094 拨打

邮箱：marketing@targetmol.com

产品详情:

中文名称：: 碘苷

英文名称：: Idoxuridine

CAS号：: 54-42-2

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 99.62%

产品类别：: 抑制剂

货号：: T0863

Product Introduction

Bioactivity

名称	Idoxuridine
描述	Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
细胞实验	The CRFK cells are cultured in 25-cm2 flasks that contained DMEM with 10% FBS. The concentration of idoxuridine is 5, 10, and 50 μM. Cells from 1 control flask and 1 flask containing each drug concentration are examined by use of an inverted microscope to detect morphologic changes and evaluate confluence, and cells are then harvested at 24, 48, and 72 hours. Culture medium is decanted, and the monolayer is rinsed once with PBS solution. Cells are then enzymatically detached with trypsin-EDTA solution. Trypsinization is stopped by the addition of DMEM with 10% FBS, and cells are forcefully pipetted to ensure complete detachment from the flasks. Each flask is then rinsed once with DMEM with 10% FBS, and the eluent is combined with the first cell suspension to ensure collection of as many cells as possible from each flask. Cell-containing medium is centrifuged (300 X g for 6 minutes), and the supernatant is decanted. Cells are then resuspended in a known volume of DMEM and counted on a hemacytometer. Cells cultured in each drug concentration at each time point are counted twice, and the total number of cells in each flask is calculated. (Only for Reference)
体外活性	Idoxuridine is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing.Idoxuridine is used for topical treatment of herpetic eye infections due to herpes simplex virus (HSV)[2].
存储条件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
溶解度	DMSO : 45 mg/mL (127.08 mM) Ethanol : < 1 mg/mL (insoluble or slightly soluble)
关键字	inhibit \| SKF-14287 \| Feline herpesvirus \| NSC-39661 \| Orthopoxvirus \| Iodinated thymidine analogue \| SKF14287 \| DNA polymerase \| Inhibitor \| Phosphatase \| IdUrd \| Herpesviruses \| Phosphorylases inhibitor \| Antiviral agents \| Idoxuridine \| NSC39661
相关产品	Oxyresveratrol \| Acyclovir \| Sodium orthovanadate \| Stearic acid \| Tartaric acid disodium dihydrate \| Cyclosporine \| 2-Deoxy-D-glucose \| Chlorhexidine diacetate \| Metronidazole \| L-Lysine \| β-Glycerophosphate disodium salt pentahydrate \| Rifampicin
相关库	抑制剂库 \| 抗癌活性化合物库 \| 抗癌上市药物库 \| 抗病毒库 \| 药物功能重定位化合物库 \| 抗癌临床化合物库

碘苷|||IDU|||SKF 14287|||5-Iodo-2′-deoxyuridine|||NSC 39661|||5-IUdR|||Dendrid|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(12年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子