1,2,4,5-苯四胺四盐酸盐|T7119|TargetMol

Y15
4506-66-5

￥197 5mg 起订

￥327 10mg 起订

￥512 25mg 起订

上海更新日期：2024-09-24

TargetMol中国（陶术生物）

VIP12年

联系人：邵小姐

电话：021-021-33632979拨打

手机：15002134094 拨打

邮箱：marketing@targetmol.com

产品详情:

中文名称：: 1,2,4,5-苯四胺四盐酸盐

英文名称：: Y15

CAS号：: 4506-66-5

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 98%

产品类别：: 抑制剂

货号：: T7119

Product Introduction

Bioactivity

Name	Y15
Description	Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity, blocks tumor growth.
Cell Research	Apoptosis assay was done with PE Annexin V Apoptosis Detection Kit (BD) to identify apoptotic nuclei.?One hundred millimeter plates were seeded with TPC1, K1, BCPAP and TT cells at a concentration of 1 × 10^6 cells in normal growth media.?After overnight incubation, plates were treated with one of several doses of Y15 or left untreated.?After another 24 h of incubation, cells were collected with trypsin, and following centrifugation, were washed with 1× PBS.?Again, cells were centrifuged, PBS was removed and cells were resuspended in binding buffer and filtered through BD mesh tubes.?Annexin V and 7-AAD were added to the solution, vortexed and incubated for 15 minutes in the dark.?Binding buffer was added and the cells were analyzed by flow cytometry within 1 hour.
In vitro	Y15 inhibited viability in ?thyroid cancer cell lines in a dose-dependent manner[1].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	H2O : 59 mg/mL (207.74 mM), Sonication and heating are recommended.
Keywords	PTK2 protein tyrosine kinase 2 \| FAK Inhibitor-14 \| FAK Inhibitor14 \| Y-15 \| FAK \| PTK2 \| Focal adhesion kinase \| Y15 \| Y 15 \| Inhibitor \| inhibit \| FAK inhibitor Y15
Inhibitors Related	PF-573228 \| Ifebemtinib \| PF-562271 \| Fangchinoline \| Roslin 2 bromide \| Ifebemtinib FA \| Masitinib \| FAK-IN-10 \| Defactinib \| Chloropyramine hydrochloride
Related Compound Libraries	Inhibitor Library \| Angiogenesis related Compound Library \| Bioactive Compound Library \| Anti-Cancer Active Compound Library \| Anti-Cancer Compound Library \| Bioactive Compounds Library Max \| Kinase Inhibitor Library \| Cytoskeletal Signaling Pathway Compound Library \| NO PAINS Compound Library \| Tyrosine Kinase Inhibitor Library

FAK Inhibitor 14|||1,2,4,5-苯四胺四盐酸盐|||1,2,4,5-Benzenetetramine tetrahydrochlor|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(12年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子