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  • 夫西地酸|T1160|TargetMol

夫西地酸|T1160|TargetMol

Fusidic acid
6990-06-3
140 100mg 起订
上海 更新日期:2026-02-25

TargetMol中国(陶术生物)

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产品详情:

中文名称:
夫西地酸
英文名称:
Fusidic acid
CAS号:
6990-06-3
品牌:
TargetMol
产地:
美国
保存条件:
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
纯度规格:
99.46%
产品类别:
抑制剂
货号:
T1160

Product Introduction

Bioactivity

名称Fusidic acid
描述Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.
激酶实验DHODase activity is measured by the DCIP colorimetric assay. This is a coupled assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent to the reduction of DCIP. Reduction of DCIP is accompanied by a loss of absorbance at 610 nm (ε=21500 M/cm). The assay is performed in a 96-well microtiter plate at ambient temperature (ca. 25°C). Stock solutions of 10 mM leflunomide and A771726 are prepared in dimethyl sulfoxide (DMSO) and these are diluted with reaction buffer (100 mM Tris and 0.1 % Triton X-100, pH 8.0) to prepare working stocks of the inhibitors at varying concentrations. For each reaction, the well contained 10 nM DHODase, 68 μM DCIP, 0.16 mg/mL gelatin, the stated concentration of ubiquinone, 10 μL of an inhibitor working stock to give the stated final concentration, and reaction buffer. After a 5-min equilibration period, the reaction is initiated by addition of DHO to the stated final concentrations. The total volume of reaction mixture for each assay is 150 μL, and the final DMSO concentration is ≤ 0.01% (v/v). The reaction progress is followed by recording the loss of absorbance at 610 nm over a 10-min period (during which the velocity remained linear). Velocities are reported as the change in absorbance at 610 nm per minute, and each reported value is the average of three replicates. In experiments where the DHO or ubiquinone concentration is varied, the other substrate is held constant at 200 μM. To determine the inhibitor potency of leflunomide and A771726, the effects of varying concentrations of the two compounds on the initial velocity of the DHODase reaction is measured over a concentration range of 0.01?1.0 μM. In these experiments the DHO and ubiquinone concentrations are held constant at 200 and 100 μM, respectively.
存储条件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.87 mM), Sonication is recommended.
DMSO : 45 mg/mL (87.09 mM), Sonication is recommended.
关键字steroids | SQ-16603 | SQ16603 | SQ 16603 | ribosome | Inhibitor | inhibit | growth | Fusidic acid | Fusidate | factor | elongation factor G (EF-G) | elongation | CAT | bacteriostatic | Bacterial | Antibiotic
相关产品Adipic dihydrazide | Levulinic acid | Doxycycline | Neomycin sulfate | BES | Terbinafine hydrochloride | Metronidazole | Copper(Ⅱ) Sulfate | Sodium diacetate | Sulfamethoxazole sodium | Kanamycin sulfate | D(+)-Raffinose pentahydrate
相关库微生物天然产物库 | 经典已知活性库 | 已知活性化合物库 | 抗生素库 | 天然产物库 | 免疫/炎症分子化合物库 | 药物功能重定位化合物库 | 萜类天然产物库 | 高通量筛选天然产物库 | 共价抑制剂库 | 人代谢物化合物库 | 抗感染天然产物库
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夫西地酸|||Fusidine|TargetMol

公司简介

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起,为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部,化学事业部,生物事业部和新材料部。 从虚拟筛选到实体化合物分子供应;从商业化产品销售到个性化定制合成;从对明确靶点的分子筛选到对明确分子的多靶点筛选,从高通量筛选到化学结构优化,我们都可以满足您的科研用品及技术服务的需求。 经过在中国市场五年的精心耕耘,我们已成为筛选化合物领域优秀的供应商,为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期 (13年)
注册资本 566.2651万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,试剂,定制,服务
主营行业 化学试剂,生物活性小分子

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