单克隆Anti-Rotavirus A VP4抗体, Human IgG1 (4D2)

Monoclonal Anti-Rotavirus A VP4 Antibody, Human IgG1 (4D2)

抗体来源（Source）

Monoclonal Anti-Rotavirus A VP4 Antibody, Human IgG1 (4D2) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.

克隆号（Clone）

4D2

亚型（Isotype）

Human IgG1 | Human Kappa

偶联（Conjugate）

Unconjugated

抗体类型（Antibody Type）

Recombinant Monoclonal

种属反应性（Reactivity）

Virus

免疫原（Immunogen）

Recombinant Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP4 Protein is expressed from human 293 cells.

特异性（Specificity）

Specifically recognizes Rotavirus A VP4.

应用（Application）

纯度（Purity）

>95% as determined by SDS-PAGE.

纯化（Purification）

Protein A purified / Protein G purified

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

Rotavirus is the leading cause of severe, watery diarrhea in infants and children less than 5 years old. It is estimated that around three-quarters of infants and children had rotavirus diarrhea before the age of 12 months and over millions of them were hospitalized due to the rotavirus infection. The rotavirus has various structural viral protein (VPs) and non-structural protein (NSPs), among them, the VP4 and VP7 together determines the serotypes of the virus, with the VP4 determines the P-type and VP-7 determines the G-type. The reassortment of these proteins leads to the diversity of the rotavirus strains, making the VP4 and VP7 the important target for vaccine studies.