Human CD9 Full Length Protein (VLP)

Human CD9 Full Length Protein (VLP)

分子别名（Synonym）

CD9,MIC3,TSPAN29,GIG2,MRP1,BTCC1,DRAP27,5H9

表达区间及表达系统（Source）

Human CD9 Full Length Protein (VLP) (CD9-H52P3) is expressed from human 293 cells (HEK293). It contains AA Pro 2 - Val 228 (Accession # P21926).

Predicted N-terminus: Met

蛋白结构（Molecular Characterization）

Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.

The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.

制剂（Formulation）

The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).

Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

运输（Shipping）

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储（Storage）

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

The product MUST be stored at -70°C or lower upon receipt;

-70°C for 12 months under sterile conditions.

背景（Background）

CD9抗原也被称为tetraspanin-29（TSPAN29）、5H9抗原、白细胞抗原MIC3（MIC3）、运动相关蛋白，是一种多通道膜蛋白，属于tetraspanin（TM4SF）家族或跨膜4超家族。CD9是一种已知与整合素和其他跨膜4超家族蛋白复合的细胞表面糖蛋白。TSPAN29存在于外泌体的表面。MIC3参与血小板活化和聚集，调节偏执连接的形成，还参与细胞粘附、细胞运动和肿瘤转移。CD9抗原似乎也是哺乳动物受精过程中卵子-精子融合的关键部分。