小鼠Transferrin R2蛋白-ACROBiosystems百普赛斯

Mouse Transferrin R2 Protein, mouse IgG1 Fc Tag, low endotoxin

分子别名（Synonym）

Transferrin R2,TFR2

表达区间及表达系统（Source）

Mouse TFR2, Mouse Fc Tag (TF2-M5269) is expressed from human 293 cells (HEK293). It contains AA Arg 103 - Phe 798 (Accession # Q9JKX3-1).

Predicted N-terminus: Val

蛋白结构（Molecular Characterization）

This protein carries a mouse IgG1 Fc tag at the N-terminus.

The protein has a calculated MW of 101.1 kDa. The protein migrates as 116 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 0.1 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

转铁蛋白受体蛋白2（TFR2）是一种单程II型膜蛋白，具有蛋白酶相关（PA）结构域、M28肽酶结构域和转铁蛋白受体样二聚化结构域。TFR2基因的突变与遗传性III型血色素沉着症有关。此外，TFR2参与通过内吞作用将转铁蛋白结合的铁摄取到细胞中，尽管与转铁蛋白受体1相比，其作用较小。