血管连接蛋白 (Cx37、Cx40) 胞外环多肽/514787-21-4/Connexin mimetic peptide 40,37GAP26

Product Name：Connexin mimetic peptide 40,37GAP26

CAS No.： 514787-21-4

Synonyms：血管连接蛋白 (Cx37、Cx40) 胞外环多肽

Catalog No.：218P989

Brand：HongTide（上海鸿肽生物）

Description：Connexin mimetic peptide 40,37GAP26是由13个氨基酸组成的多肽，Connexin mimetic peptide 40,37GAP26对应于主要血管连接蛋白 (Cx37、Cx40) 胞外环的 GAP26 结构域，根据 Cx 同源性指定为 37、40Gap 26。Connexin mimetic peptide 40,37GAP26用于研究间隙连接在环吡嗪酸 (CPA) 穿过啮齿动物髂动脉壁引起的内皮超极化扩散中的作用。由 Cx37 和 Cx40 构建的间隙连接斑块在内皮细胞中含量丰富。Connexin mimetic peptide 40,37GAP26对内膜下超极化具有抑制作用。

Connexin mimetic peptide 40,37GAP26 is a peptide composed of 13 amino acids. Connexin mimetic peptide 40,37GAP26 corresponds to the GAP26 domain of the extracellular loop of major vascular junction proteins (Cx37, Cx40), designated as 37,40Cap 26 based on Cx homology. Connexin mimetic peptide 40,37GAP26 was used to investigate the role of gap junctions in endothelial hyperpolarization diffusion induced by cyclic pyrazine acid (CPA) passing through the iliac artery wall of rodents. The gap junction plaques constructed by Cx37 and Cx40 are abundant in endothelial cells. Connexin mimetic peptide 40,37GAP26 has inhibitory effects on subendothelial hyperpolarization.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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