岩藻多糖|T7544|TargetMol

Fucoidan
9072-19-9

￥286 500mg 起订

￥133 100mg 起订

上海更新日期：2024-12-02

TargetMol中国（陶术生物）

VIP12年

联系人：邵小姐

电话：021-021-33632979拨打

手机：15002134094 拨打

邮箱：marketing@targetmol.com

产品详情:

中文名称：: 岩藻多糖

英文名称：: Fucoidan

CAS号：: 9072-19-9

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: ≥98%

产品类别：: 抑制剂

货号：: T7544

Product Introduction

Bioactivity

Name	Fucoidan
Description	Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.
Cell Research	The influence of fucoidan on B16 melanoma cells and cellular tyrosinase:Cell viability was examined by the cell counting kit-8 assay. Cellular tyrosinase activity and melanin content were determined using spectrophotometric methods and protein expression was analyzed by immunoblotting. Morphological changes in B16 melanoma cells were examined by phase contrast microscopy and apoptosis was analyzed by flow cytometry[1].
Animal Research	In vivo, therapy experiments were conducted on Babl/c mice bearing breast cancer.?The tumor volume and weight were measured.?The number of apoptotic cells and microvascular density (MVD) in tumor tissues were assessed by TUNEL and CD34 immunostaining.?Immunohistochemical assays and ELISA assay were used to detect the expression of VEGF in tissues[2].
In vitro	Fucoidan在剂量反应方式下显著减少了活细胞数量，其IC50为550 ±4.3 μg/mL。当细胞暴露于550 μg/mL的Fucoidan下48小时时，细胞形态发生了变化，并且显著诱导了凋亡[1]。
In vivo	在乳腺癌模型中通过腹腔注射fucoidan可以减少肿瘤体积和重量。提高的抗肿瘤效果与血管生成减少和凋亡诱导增加有关[2]。
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	H2O : 10 mM DMSO : Insoluble
Keywords	polysaccharide \| anticoagulant \| diabetes \| inhibit \| Glucosidase \| antisteatotic \| Inhibitor \| α-amylase \| α-glucosidase. Antioxidant \| Type 2 \| anticancer \| Fucoidan

岩藻多糖|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(12年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子