普罗瑞林|T6956|TargetMol

Protirelin
24305-27-9

￥218 1mg 起订

￥497 5mg 起订

￥749 10mg 起订

上海更新日期：2026-01-06

TargetMol中国（陶术生物）

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联系人：邵小姐

电话：021-021-33632979拨打

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产品详情:

中文名称：: 普罗瑞林

英文名称：: Protirelin

CAS号：: 24305-27-9

品牌：: TargetMol

产地：: 美国

保存条件：: keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

纯度规格：: 99.76%

产品类别：: 抑制剂

货号：: T6956

Product Introduction

Bioactivity

名称	Protirelin
描述	Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.
动物实验	Protirelin (TRH tartRatse) is dissolved in physiological saline (Rats).RatsNinety male Wistar rats weighing 200-250 g are subjected to the study. In the first experiment, 50 rats are divided into five groups randomly. Four doses of Protirelin dissolved in physiological saline, i. e., 1 mg/kg, 5 mg/kg, 10 mg/kg and 20 mg/kg, are administered intraperitoneally to the four groups and saline to the remaining control group. Rectal temperature is measured at the place 5 cm inner from the anus with the electronic thermister before and after treatment with Protirelin or saline. In the second experiment, 40 rats are thyroidectomized or sham-operated under the anesthesia by thiopental sodium. Ten days after the operation, 20 mg/kg of Protirelin or saline is administered to the thyroidectomized and sham-operated animals by i. p. and rectal temperature is measured using the same method as used in the first experiment. These two experiments are undertaken from 1 p, m, to 4 p. m. and the room temperature is kept at 24±1°C through the experiments including the breeding period. For a statistical analysis, Student's t test (two-tailed) is adopted.
体内活性	Protirelin (TRH) 是一种神经肽，在原口动物和后口动物分化之前就已存在。Protirelin 可能原本与控制胚胎后生长和繁殖有关。研究探讨了下丘脑释放激素之一的促甲状腺激素释放激素（Protirelin, TRH）对大鼠体温的影响。通过腹腔注射1, 5, 10和20 mg/kg的Protirelin给体重在200-250 g的雄性Wistar大鼠，结果显示Protirelin 能够依剂量暂时提高体温。在注射了20 mg/kg Protirelin的甲状腺切除大鼠中，相较于假手术动物的显著高热反应，这些大鼠未显示出体温上升。当前结果暗示甲状腺激素的释放可能参与了Protirelin的高热作用。
存储条件	keep away from moisture,store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度	Ethanol : 67 mg/mL (184.89 mM), Sonication is recommended. DMSO : 67 mg/mL (184.89 mM), Sonication is recommended. H2O : 66 mg/mL (182.13 mM), Sonication is recommended.
关键字	Thyroidhormonereceptor(THR) \| Thyroidhormonereceptor \| Thyroid hormone receptor(THR) \| Thyroid hormone receptor \| Thyroid Hormone Receptor \| THR \| Protirelin \| Inhibitor \| inhibit \| EndogenousMetabolite \| Endogenous Metabolite
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普罗瑞林|||TRH|||TRF|||Thyroliberin|||Synthetic thyrotropin-releasing hormone|||pGlu-His-Pro-NH2|||Lopremone|TargetMol

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成立日期	(13年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子