夫西地酸钠|T1289

Fusidic acid sodium salt
751-94-0

￥397 200mg 起订

￥282 100mg 起订

￥638 500mg 起订

上海更新日期：2024-09-15

TargetMol中国（陶术生物）

VIP12年

联系人：邵小姐

电话：021-021-33632979拨打

手机：15002134094 拨打

邮箱：marketing@targetmol.com

产品详情:

中文名称：: 夫西地酸钠

英文名称：: Fusidic acid sodium salt

CAS号：: 751-94-0

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 99.17%

产品类别：: 抑制剂

货号：: T1289

Product Introduction

Bioactivity

名称	Fusidic acid sodium salt
描述	Fusidic acid sodium salt (SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
激酶实验	Binding assays: Binding assays are performed as previously described (Allenby et al., 1993, 1994). Briefly, labeled and unlabeled retinoids are added to nucleosol or cytosolic fractions in ethanol so that the total amount of ethanol added is constant in all tubes and did not exceed 2% of the incubation volume. The receptor preparations are incubated with retinoids at 4°C for 4–6 hr. Sephadex PD-10 desalting columns are used to separate bound radioligand from free radioligand after equilib- rium is achieved. For competitive binding assays, varying concentrations of unlabeled competing ligand are incubated with the appropriate nucleosol or cytosol in the presence of a fixed concentration of [3H]tRA (sp. act. 49.3 Ci/mmol) or [3H]9-cis RA (sp. act. 24.0 Ci/mmol). Final concentrations of [3H] tRA and [3H]9-cis RA for nuclear receptor binding assays are 5 nM. Final concentrations of [3H] tRA for CRABP binding assays is 30 nM. The IC50s are calculated as described above (DeLean et al., 1978). For saturation kinetics, increasing concentrations of radiolabeled ligand ([3H]tRA sp. act. 49.3 Ci/mmol, [3H]TTNPB sp. act. 5.5 Ci/ mmol) are added to the nucleosol of the appropriate receptor subtype in the presence (nonspecific binding) or absence (total binding) of a 100-fold molar excess of the corresponding unlabeled retinoid. Specific binding is defined as the total binding minus nonspecific binding. Saturation kinetics are calculated as previously described (Scatchard, 1949; Grippo and Gudas, 1987; Levin et al., 1992).
体内活性	Fusidin（Fusidate Sodium）至少在一定程度上通过抑制TNF-α的分泌改善EAM[1]。Fusidin显著减轻了给予链脲佐菌素（SZ）的小鼠免疫炎症糖尿病的临床和组织学征象。该作用是剂量依赖性的，且在三个不同的小鼠品系中均有观察到。因此，Fusidin 可能具有抗糖尿病效应[2]。
存储条件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
溶解度	Ethanol : 93 mg/mL (172.6 mM) H2O : 92 mg/mL (170.8 mM) DMSO : 93 mg/mL (172.6 mM)
关键字	bacteriostatic \| ribosome \| Fusidic acid \| Bacterial \| factor \| Inhibitor \| SQ 16360 \| Fusidic acid sodium salt \| Antibiotic \| growth \| elongation \| inhibit \| steroids \| SQ16360 \| Fusidic acid sodium
相关产品	Neomycin sulfate \| Dimethyl sulfoxide
相关库	微生物天然产物库 \| 抑制剂库 \| 经典已知活性库 \| 已知活性化合物库 \| 天然产物库 \| 药物功能重定位化合物库 \| 高通量筛选天然产物库 \| 抗感染天然产物库

Sodium fusidate|||夫西地酸钠|||Fusidate Sodium|||Fucidin|||SQ-16360|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(12年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子