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  • 替诺福韦酯|T7111

替诺福韦酯|T7111

Tenofovir Disoproxil
201341-05-1
147 5mg 起订
213 10mg 起订
340 25mg 起订
上海 更新日期:2026-01-06

TargetMol中国(陶术生物)

VIP13年
联系人:邵小姐
电话:021-021-33632979拨打
手机:15002134094 拨打
邮箱:marketing@targetmol.com

产品详情:

中文名称:
替诺福韦酯
英文名称:
Tenofovir Disoproxil
CAS号:
201341-05-1
品牌:
TargetMol
产地:
美国
保存条件:
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
产品类别:
抑制剂
货号:
T7111

Product Introduction

Bioactivity

名称Tenofovir Disoproxil
描述Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
细胞实验Human immortalized epithelial HK-2 cells were grown in a keratinocyte-free media with 50 μg/mL bovine pituitary extract and 5 ng/mL recombinant epithelial growth factor from Invitrogen. Cells were grown in a warm humidified incubator with constant settings of 37 °C and 5% CO2. HK-2 cells were plated into six-well tissue culture plates (750,000 cells/mL) and allowed to grow for 48 h. Media was replaced and cells were treated with a final concentration of 0, 1.5, 3.0, 4.75, 14.5, or 28.8 μM TFV for 24, 48, or 72 h. The vehicle was an equal volume of phosphate buffered saline (PBS). Abacavir was prepared in sterile water and cells were treated for 24 h with 0, 1.5, 3 or 6 μM of abacavir to evaluate renal sensitivity to an agent recognized to be less nephrotoxic. Following the treatment period, cells were collected with Trypsin-EDTA (0.25%) for sample analysis[1].
存储条件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.85 mM), Sonication is recommended.
DMSO : 45 mg/mL (86.63 mM), Sonication is recommended.
关键字Tenofovir Disoproxil | ReverseTranscriptase | Reverse Transcriptase | Inhibitor | inhibit | Human immunodeficiency virus | HIVProtease | HIV Protease | HIV | Hepatitis B virus | HBV | GS-4331 | GS4331
相关产品Valproic Acid | Nicotinamide | (-)-Epigallocatechin Gallate | Dimethyl fumarate (Standard) | Emtricitabine | Dextran sulfate sodium salt (MW 5000) | Lamivudine | 5-Fluorouracil | Decanedioic acid | Stavudine | Lysozyme from chicken egg white | 3-Hydroxypyridine
相关库抑制剂库 | 核苷类化合物库 | 经典已知活性库 | 已知活性化合物库 | EMA 上市药物库 | 上市药物库 | NO PAINS 化合物库 | FDA 上市药物库 | 抗病毒库 | 免疫/炎症分子化合物库 | 药物功能重定位化合物库 | 人代谢物化合物库
替诺福韦酯|||GS 4331|||Bis(POC)-PMPA|TargetMol

公司简介

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起,为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部,化学事业部,生物事业部和新材料部。 从虚拟筛选到实体化合物分子供应;从商业化产品销售到个性化定制合成;从对明确靶点的分子筛选到对明确分子的多靶点筛选,从高通量筛选到化学结构优化,我们都可以满足您的科研用品及技术服务的需求。 经过在中国市场五年的精心耕耘,我们已成为筛选化合物领域优秀的供应商,为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期 (13年)
注册资本 566.2651万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,试剂,定制,服务
主营行业 化学试剂,生物活性小分子

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