化合物 D-Lin-MC3-DMA|T5823

D-Lin-MC3-DMA
1224606-06-7

询价 1removed 起订

上海更新日期：2026-05-08

TargetMol中国（陶术生物）

VIP14年

联系人：邵小姐

电话：021-021-33632979拨打

手机：15002134094 拨打

邮箱：marketing@targetmol.com

产品详情:

中文名称：: 化合物 D-Lin-MC3-DMA

英文名称：: D-Lin-MC3-DMA

CAS号：: 1224606-06-7

品牌：: TargetMol

产地：: 美国

保存条件：: Keep away from moisture,Store at low temperature,Keep away from direct sunlight Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

纯度规格：: 99.69%

产品类别：: 抑制剂

货号：: T018|T5823

Product Introduction

Bioactivity

名称	D-Lin-MC3-DMA
描述	D-Lin-MC3-DMA is a siRNA delivery vector, an ionizable amino-lipid compound. D-Lin-MC3-DMA offers advantages of high loading efficiency, low toxicity, and efficient endosomal escape.
细胞实验	White leghorn chicken embryos at stage 24 (30) were removed and dissected in Hanks buffered saline solution (HBSS).?Forelimbs were pooled and treated for 1 h in dispase to remove epithelial ectoderm.?Limb mesenchyme was dissociated, and resuspended in DMEM with 5% FBS and 1% penicillin/streptomycin.?Cells were plated onto 96-well plates at a density of 2x10^5 or 2x10^7 cells/ml and treated with 0-40 μg/ml LNP-pDNA.?Cultures were incubated overnight at 37℃ and resuspended in PBS buffer for expression analysis using a BD LSRII flow cytometer.?Cell survival was assessed in low-density cultures after 24 h of treatment, by counting the adherent cells remaining after PBS washes.?Viability was determined based on average counts of all adherent cells within a single field of view (100x) normalized to cell counts of untreated cultures.
体外活性	将DSPC替换为不饱和PCs，并将DLin-MC3-DMA替换为相关脂质DLin-KC2-DMA，可显著提高HeLa细胞体外转染试剂的效能。
存储条件	Keep away from moisture,Store at low temperature,Keep away from direct sunlight Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
溶解度	Ethanol : 16.67 mg/mL (25.96 mM), Sonication and heating are recommended. DMSO : 43.33 mg/mL (67.48 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.11 mM), Sonication is recommended.
关键字	Inhibitor \| inhibit \| D-Lin-MC3-DMA \| D-Lin-MC-3-DMA \| DLinMC3DMA \| D Lin MC3 DMA
相关产品	Cholesterol \| Benzyl nicotinate \| DOPE \| DSPS \| 1,2-Distearoyl-sn-glycero-3-phosphorylcholine \| Phosphatidylcholines,soya \| Dimethyldioctadecylammonium (bromide) \| DMG-PEG 2000 \| 1,2-Dierucoyl-sn-glycero-3-PC \| DOTAP chloride \| DODAP \| Stearamide
相关库	经典已知活性库 \| 已知活性化合物库 \| 活性脂质化合物库 \| NO PAINS 化合物库 \| 抗COVID-19化合物库

D-Lin-MC3-DMA;TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(14年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子