替拉那韦替拉那韦174484-41-4

中文名称替拉那韦中文同义词替拉那韦;N-[3-[(1R)-1-[(6R)-2-羟基-4-氧代-6-苯乙基-6-丙基-5H-吡喃-3-基]丙基]苯基]-5-(三氟甲基)吡啶-2-磺酰胺;替拉那韦杂质1;N-(3-((R)-1-((R)-4-羟基-2-氧代-6-苯乙基-6-丙基-5,6-二氢-2H-吡喃-3-基)丙基)苯基)-5-(三氟甲基)吡啶-2-磺酰胺;N-(3-((R)-1-((R)-4-羟基-2-氧代-6-苯乙N-(3-((R)-1-((R)-4-羟基-2-氧代-6-苯乙基-6-丙基-5,6-二氢-2H-吡喃-3-基)丙基)苯基)-5-(三氟甲基)吡啶-2-磺酰胺基-6-丙基-5,6-二氢-2H-吡喃-3-基)丙基)苯基)-5-(三氟甲基)吡英文名称Tipranavir英文同义词Tipranavir(TPV);TIPRANAVIR(PNU-140690);N-[3-[(1R)-1-[(2R)-4-HYDROXY-6-OXO-2-(2-PHENYLETHYL)-2-PROPYL-3H-PYRAN-5-YL]PROPYL]PHENYL]-5-(TRIFLUOROMETHYL)PYRIDINE-2-SULFONAMIDE;PNU-140690;Aptivus;N-[3-[(1R)-1-[(6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinesulfonamide;N-[3-[(1R)-1-[(6R)-2-Hydroxy-4-oxo-6-phenethyl-6-propyl-5H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide;TipranavirCAS号174484-41-4分子式C31H33F3N2O5S分子量602.66EINECS号相关类别医药中间体;抗病毒类;AllInhibitors;Inhibitors;Intermediates&FineChemicals;Pharmaceuticals;AntiviralAgentsMol文件174484-41-4.mol

抗病毒药替拉那韦，西药名。常用剂型有胶囊剂等。为抗病毒药。合用利托那韦对具有病毒复制、并已治疗时间很长或感染HIV-1面又耐多种蛋白酶抑制剂的成年患者进行治疗。生物活性Tipranavir(PNU-1Chemicalbook40690)有效抑制HIV-1蛋白酶酶活性和二聚化，对抗多种蛋白酶抑制剂(PI)的HIV-1分离株具有有效的活性，IC50为66-410nM。靶点IC50:66-410nM(HIV-1isolates)