产品名称 人参皂苷 Compound K
英文名称 Ginsenoside Compound K
植物拉丁名 Panax ginseng C.A. Meyer
科 五加科
属 人参属
使用部位 根
介绍
人参皂苷(Ginsenoside)是人参及其同属植物(三七、西洋参等)的主要药理活性成份,目前已分离出40余种人参皂苷单体。人参皂苷CK属二醇型皂苷,它在天然人参中的含量极低,但它是其它含量较高人参皂苷Rb1和Rb2等在人体肠道内的主要降解产物和最终吸收形式,具有很高的生物活性。
性状
本品为棕黄色粉末。
可供规格
- 1.5%HPLC,适用于特殊及癌症病患的食品
- 0.15%HPLC,适用于一般食品
人参皂苷CK的优势
1.“天然前药”理论已经证实人参皂苷CK是人参皂苷活性作用的实体,现有研究表明其抗肿瘤和增强免疫活性是所有人参皂苷中最强的;
2. 人参皂苷CK在所有人参皂苷中最适宜作为抗肿瘤药用开发。人参皂苷CK具有良好的水溶液性,而人参皂苷Rg3、Rh1、Rh2水溶性极差。对恶性肿瘤患者而言,一旦进入常规治疗,消化系统功能基本完全丧失,对口服制剂吸收水平相当有限,人参皂苷CK可以凭其良好水溶性制成注射液直接发挥作用;
3.人参皂苷CK介入具体抗肿瘤药物治疗方案,有助于建立高效的肿瘤治疗模式,挖掘现有治疗手段和药物的治疗潜力。现有研究表明,人参皂苷CK确实对某些一线抗肿瘤药物具有良好减毒增效作用
药理功能
1.抗肿瘤:人参皂苷CK抗肿瘤机制主要表现以下几点:A抑制肿瘤细胞增殖;B促进肿瘤细胞凋亡;C抑制肿瘤细胞侵入和转移;D提高化疗药物对肿瘤细胞的敏感性,减轻其对正常细胞的毒副作用
2. 抗糖尿病,调节血糖
3. 免疫调节
4. 抗过敏、发炎
5. 抗高血压
6. 皮肤保湿
应用领域
医药原料 、保健品、食品和饮料 、化妆品
Product Name: Ginsenoside Compound K
Latin Name in Botany: Panax ginseng C.A. Meyer
Family: Araliaceae
Genus: Panax
Used Part: Root
Introduction:
Ginsenoside is the main pharmacological active ingredient of panax ginseng and its the same family plants (Panax notoginseng, American ginseng, etc.). It has been separated more than 40 kinds of ginseng saponin monomer. Ginsenoside CK belongs to diol-type saponins, which is very low in natural ginseng. But it is the main degradation products and the final absorptional form of other high content ginsenosides, like ginsenoside Rb1 and Rb2, ect. Ginsenoside CK has a high biological activity.
Character: Brown yellow powder
Available specifications:
1, 1.5% HPLC, apply to special foods and cancer patients
2, 0.15% HPLC, apply to general food
The advantages of Ginsenoside CK:
1. "Natural prodrug" theory has been confirmed Ginsenoside CK is the entity of Ginsenosides active role. The existing research shows that the anti-tumor activity and enhance immune of Ginsenoside CK is the strongest of all ginsenosides;
2 Ginsenoside CK ginsenosides is the most suitable to use as anti-tumor development in all ginsenosides. It has a good solution, while ginsenoside Rg3, Rh1, Rh2 are in poor water solubility. For cancer patients, once into the conventional treatment, digestive function was completely lost. Preparations for oral absorption level is very limited. But ginsenoside CK can be made into injection, with its good water solubility, to play a direct role.
3 Ginsenoside CK, intervening specific antineoplastic treatment programs, is help to build efficient cancer treatment modalities, to explore the existing treatments and therapeutic potential. The existing studies have shown that ginsenosides CK indeed has a good synergistic effect attenuation for some first-line anticancer drugs.
Pharmacological functions:
1 anti-tumor:
Following is the main points of Ginsenoside CK anti-tumor mechanism:
A inhibition of tumor cell proliferation;
B to promote tumor cell apoptosis;
C inhibition of tumor cell invasion and metastasis;
D to improve chemotherapy sensitivity of tumor cells, reducing its impact on normal cells side effects
2 anti-diabetic, regulate blood sugar
3 immunomodulatory
4 anti-allergic, anti-inflammatory
5 anti-hypertensive
6 Skin Moisturizer
Applications: Pharmaceutical raw materials, Health products, Food and Beverages, Cosmetics