重组人HE4蛋白-ACROBiosystems百普赛斯

Human HE4 / WFDC2 Protein, His Tag

分子别名（Synonym）

HE4,WAP5,WFDC2,EDDM4

表达区间及表达系统（Source）

Human HE4, His Tag (HE4-H5223) is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Phe 124 (Accession # AAH46106).

Predicted N-terminus: Glu 31

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 10.9 kDa. The protein migrates as 19-23 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

人附睾蛋白4（HE4）也称为WAP四二硫键核心结构域蛋白2（WFDC2）、附睾分泌蛋白E4、主要附睾特异性蛋白E4、推测蛋白酶抑制剂WAP5，是WFDC结构域家族的成员。HE4/WFDC2在肺上皮细胞中表达，也在一些卵巢癌中表达。WFDC结构域或WAP签名基序包含八个半胱氨酸，在蛋白质的核心形成四个二硫键，在许多家族成员中起蛋白酶抑制剂的作用。HE4也是一种小的分泌蛋白，可能参与精子成熟。